Nathan Usry
University of Mississippi Medical Center
9 Papers
29 Citations
Nathan Usry is an academic researcher from University of Mississippi Medical Center. The author has contributed to research in topics: Preeclampsia & Oxidative stress. The author has an hindex of 7, co-authored 7 publications. Previous affiliations of Nathan Usry include University of Mississippi.
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Papers
Role of Mitochondrial Dysfunction and Reactive Oxygen Species in Mediating Hypertension in the Reduced Uterine Perfusion Pressure Rat Model of Preeclampsia.
Venkata Ramana Vaka,Kristen M. McMaster,Mark W. Cunningham,Tarek Ibrahim,Rebekah Hazlewood,Nathan Usry,Denise C. Cornelius,Lorena M. Amaral,Babbette LaMarca +8 more
TL;DR: The purpose of this study was to not only examine the effect of placental ischemia on mitochondrial-mediated oxidative stress in reduced uterine perfusion pressure (RUPP) rat model of preeclampsia but to also examine the role of mitochondrial ROS in contributing to hypertension in response to placentalIschemia.
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Renal natural killer cell activation and mitochondrial oxidative stress; new mechanisms in AT1-AA mediated hypertensive pregnancy.
Mark W. Cunningham,Venkata Ramana Vaka,Kristen M. McMaster,Tarek Ibrahim,Denise C. Cornelius,Lorena M. Amaral,Nathan Campbell,Gerd Wallukat,Shyanne McDuffy,Nathan Usry,Ralf Dechend,Babbette LaMarca +11 more
TL;DR: It is hypothesized that AT1-AA induced model of PE will exhibit elevated MAP, NK cells, and mtROS; while inhibition of the AT2-AA binding to the AT1R would be preventative; and the role of NK cells and mitochondrial reactive oxygen species in AT 1-AA mediated hypertension during pregnancy is unknown.
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Vitamin D supplementation reduces some AT1-AA-induced downstream targets implicated in preeclampsia including hypertension
Jessica L. Faulkner,Lorena M. Amaral,Denise C. Cornelius,Mark W. Cunningham,Tarek Ibrahim,Autumn Heep,Nathan Campbell,Nathan Usry,Kedra Wallace,Florian Herse,Ralf Dechend,Babbette LaMarca +11 more
TL;DR: VD2 and/or VD3 improved PE features associated with AT1-AA during pregnancy, while ANG II did not induce such features, supporting the hypothesis that AT 1-AA induces PE features duringregnancy, and these are improved with vitamin D.
Blockade of endogenous angiotensin II type I receptor agonistic autoantibody activity improves mitochondrial reactive oxygen species and hypertension in a rat model of preeclampsia
Venkata Ramana Vaka,Mark W. Cunningham,Evangeline Deer,Michael Franks,Tarek Ibrahim,Lorena M. Amaral,Nathan Usry,Denise C. Cornelius,Ralf Dechend,Gerd Wallukat,Babbette LaMarca +10 more
TL;DR: The findings suggest that AT1-AA signaling is one stimulus of mtROS during PE, and endothelial cells (HUVECs) treated with RUPP+'n7AAc' sera exhibited lessmtROS compared to those treated withRUPP sera.