Nathan A. Salomonis
15 Papers
Nathan A. Salomonis is an academic researcher. The author has contributed to research in topics: Gene & Internal medicine. The author has co-authored 1 publications.
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Papers
An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors.
Xuan Zhang,MJ Carlino,Guangyuan Li,Kyle Ferchen,Mi Chen,Evrett N. Thompson,Bailee N Kain,Dan Schnell,Kairavee Thakkar,Michal Kouril,Kang Jin,Stuart Hay,Sidharth Sen,David Bernardicius,Siyuan Ma,Sierra Bennett,Josh Croteau,O. Salvatori,Melvin H Lye,Austin Gillen,Craig T. Jordan,Harinder Singh,Diane S Krause,Nathan A. Salomonis,H. L. Grimes +24 more
TL;DR: Researchers created a comprehensive atlas of human hematopoietic progenitors using CITE-seq, identifying over 80 distinct cell types and surface markers, and nominating normal marrow equivalents for acute myeloid leukemia stem cells.
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De Novo Germline DHX38 Variant Associated with Alternative Splicing of Multiple Transcripts in Iron-Related Pathways in a Patient with Atypical Congenital Dyserythropoietic Anemia with Ring Sideroblasts
Aikaterini Voulgaridou,Yasmin Elgammal,Ammar Husami,Sana Emberesh,Katie Giger Seu,Mahesh Ramamoorthy,Lisa Trump,Nathaniel Barasa,Adam S. Nelson,Robert B. Lorsbach,Laurel Romano,Nathan A. Salomonis,Wenying Zhang Zhang,Carolyn Lutzko,Theodosia A. Kalfa +14 more
TL;DR: A 2-year-old female, enrolled in CDAR, had transfusion-dependent anemia since birth and had failure to thrive despite regular transfusions maintaining trough hemoglobin higher than 9.5 g/dL as mentioned in this paper .
RNA Isoforms as Broad Targets for Cancer Immunotherapy.
Guangyuan Li,Nathan A. Salomonis +1 more
TL;DR: RNA isoforms are broadly targeted for cancer immunotherapy, offering new and emerging technologies for cancer treatment.
Genotype-immunophenotype relationships in NPM1-mutant AML clonal evolution uncovered by single cell multiomic analysis
Morgan Drucker,Darren Lee,Xuan Zhang,Bailee Kain,Michael Bowman,Deedra Nicolet,Zhe Wang,R. Stone,Krzysztof Mrózek,Andrew J Carroll,Daniel T. Starczynowski,R. L. Levine,John C. Byrd,A-K Eisfeld,Nathan A. Salomonis,H. L. Grimes,Robert L Bowman,Linde A. Miles +17 more
TL;DR: This study uses single-cell multiomic analysis to investigate clonal evolution in NPM1-mutant AML, revealing similar clonal architecture patterns at diagnosis and relapse, but increased diversity at relapse driven by signaling mutations, and unique genotype-immunophenotype relationships.
AAV-mediated silencing of Sox4 leads to long-term amelioration of liver phenotypes in mouse models of Alagille syndrome.
Duncan Fox,Jun Xie,Jennifer L. Burwinkel,Josh M. Adams,Kashish Chetal,Marzieh Keivandarian,Yaniv Faingelernt,Sanjay Subramanian,Mario F. Lopez,Anna L Peters,Nathan A. Salomonis,Neda Zarrin-Khameh,Guangping Gao,Stacey S. Huppert,Hamed Jafar-Nejad +14 more