Natalie Hiscock

TL;DR: In the post‐absorptive state, MPS is dose dependant on intensity rising to a plateau at 60–90% 1 repetition maximum (1 RM), and older men show anabolic resistance of signalling and MPS to resistance exercise.

TL;DR: It is shown that IL-6 contributes to the contraction-induced increase in endogenous glucose production (EGP), and potential new insights are provided into factors that mediate glucose production and disposal and implicates IL- 6 in the so-called "work factor."

TL;DR: Increased insulin secretion precedes the development of peripheral insulin resistance, mitochondrial dysfunction and obesity in response to overfeeding, suggesting a role for insulin per se as well GIP, in the developmentof peripheral insulin Resistance and obesity.

TL;DR: Investigation of the effect of 9 days of bed rest on basal and insulin-stimulated expression of genes potentially involved in insulin action and DNA methylation in the promoter region of the peroxisome proliferator-activated receptor-γ coactivator-1α gene concluded impaired expression of PPARGC1A and other genes involved in mitochondrial function may contribute to the development of insulin resistance induced by bed rest.