Natalia Milduberger
Universidad Abierta Interamericana
7 Papers
1 Citations
Natalia Milduberger is an academic researcher from Universidad Abierta Interamericana. The author has contributed to research in topics: Trypanosoma cruzi & Chagas disease. The author has an hindex of 4, co-authored 7 publications.
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Papers
Trypanosoma cruzi Infection at the Maternal-Fetal Interface: Implications of Parasite Load in the Congenital Transmission and Challenges in the Diagnosis of Infected Newborns.
Patricia Bustos,Natalia Milduberger,Bibiana Julieta Volta,Alina Elizabeth Perrone,Susana A. Laucella,Jacqueline Bua +5 more
TL;DR: Improvements in detection of this parasite, with tools that can be easily adapted to be used in remote rural areas, will make the early diagnosis of infected children possible, allowing a prompt trypanocidal treatment and avoiding the current loss of opportunities for the diagnosis of 100% of T. cruzi congenitally infected infants.
A homolog of cyclophilin D is expressed in Trypanosoma cruzi and is involved in the oxidative stress-damage response.
Patricia Laura Bustos,Bibiana Julieta Volta,Alina Elizabeth Perrone,Natalia Milduberger,Jacqueline Bua +4 more
TL;DR: It is described for the first time in a protozoan parasite that a mitochondrial cyclophilin is a component of the permeability transition pore and is involved in regulated cell death induced by oxidative stress.
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Improved Immuno-Detection of a Low-Abundance Cyclophilin Allows the Confirmation of its Expression in a Protozoan Parasite
Patricia Bustos,Alina Elizabeth Perrone,Natalia Milduberger,Jacqueline Búa +3 more
- 06 Oct 2015
TL;DR: The combined strategy of using more specific antibodies and increasing the presence of subcellular proteins in the sample, allowed us to confirm the expression of a 21.1 kDa cyclophilin for the first time in Trypanosoma cruzi.
A Functional Analysis of the Cyclophilin Repertoire in the Protozoan Parasite Trypanosoma Cruzi.
Alina Elizabeth Perrone,Natalia Milduberger,Alicia Graciela Fuchs,Patricia Laura Bustos,Jacqueline Bua,Jacqueline Bua +5 more
- 31 Oct 2018
TL;DR: The findings on T.cruzi cyclophilins will allow further characterization of these processes, leading to new insights into the biology, the evolution of metabolic pathways, and novel targets for anti-T.
Circulating cytokine and chemokine profiles of Trypanosoma cruzi-infected women during pregnancy and its association with congenital transmission
Bibiana Julieta Volta,Patricia Bustos,Carolina González,María Ailén Natale,Alina Elizabeth Perrone,Natalia Milduberger,Susana A. Laucella,Jacqueline Bua +7 more
TL;DR: In this paper, the authors evaluated differentially expressed factors in T. cruzi-infected pregnant women as potential markers of Chagas congenital transmission and found that high parasitemia together with low levels of tumor necrosis factor (TNF)-α, IL-15, and IL-17, low TNF-α/IL-10 ratio, and high IL-12p70 levels are factors associated with an increased probability of chagas Congenital Transmission.