Naoki Tsukimura
University of California, Los Angeles
35 Papers
62 Citations
Naoki Tsukimura is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Titanium & Osseointegration. The author has an hindex of 21, co-authored 34 publications. Previous affiliations of Naoki Tsukimura include Nihon University.
Chat about Author
Papers
Ultraviolet light-mediated photofunctionalization of titanium to promote human mesenchymal stem cell migration, attachment, proliferation and differentiation.
Hideki Aita,Wael Att,Takeshi Ueno,Masahiro Yamada,Norio Hori,Fuminori Iwasa,Naoki Tsukimura,Takahiro Ogawa +7 more
TL;DR: A novel photofunctionalization of titanium dioxide that substantially enhances its bioactivity in human MSCs is discovered, finding its significance in enhancing in vivo osteoconductivity.
177
Synergistic effects of UV photofunctionalization and micro-nano hybrid topography on the biological properties of titanium.
Naoki Tsukimura,Masahiro Yamada,Fuminori Iwasa,Hajime Minamikawa,Wael Att,Wael Att,Takeshi Ueno,Lei Saruwatari,Hideki Aita,Wen An Chiou,Takahiro Ogawa +10 more
TL;DR: It is suggested that the effect of UV photofunctionalization can be multiplied on micro-nano hybrid titanium surfaces compared with the surfaces with micropits alone, and this multiplication is disproportionately regulated by a selected set of topographical parameters of the titanium surfaces.
96
N-acetyl cysteine (NAC)-mediated detoxification and functionalization of poly(methyl methacrylate) bone cement.
Naoki Tsukimura,Masahiro Yamada,Hideki Aita,Norio Hori,Fumihiko Yoshino,Masaichi-Chang-il Lee,Katsuhiko Kimoto,Anahid Jewett,Takahiro Ogawa +8 more
TL;DR: Results suggest that incorporation of NAC in PMMA bone cement detoxifies the material by immediate and effective in situ scavenging of free radicals and increasing intracellular antioxidant reserves, and consequently adds osteoconductivity to the material.
90
Enhanced bone-integration capability of alkali- and heat-treated nanopolymorphic titanium in micro-to-nanoscale hierarchy.
TL;DR: Using an exemplary alkali- and heat-treated nanopolymorphic surface, critical parameters necessary to describe the process and consequences of bone-implant integration are identified, for which nanofeatures have specific and substantial roles beyond those of microfeatures.
84
N-acetyl cysteine as an osteogenesis-enhancing molecule for bone regeneration
Masahiro Yamada,Masahiro Yamada,Naoki Tsukimura,Takayuki Ikeda,Yoshihiko Sugita,Wael Att,Wael Att,Norinaga Kojima,Katsutoshi Kubo,Takeshi Ueno,Kaoru Sakurai,Takahiro Ogawa +11 more
TL;DR: Results indicate that NAC can function as an osteogenesis-enhancing molecule to accelerate bone regeneration by activating differentiation of osteogenic lineages.
82