Nancy Tresser
National Institutes of Health
19 Papers
374 Citations
Nancy Tresser is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Multiple sclerosis & Encephalomyelitis. The author has an hindex of 14, co-authored 19 publications.
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Papers
Vascular endothelial growth factor is expressed in multiple sclerosis plaques and can induce inflammatory lesions in experimental allergic encephalomyelitis rats.
TL;DR: The results suggest that overexpression of VEGF may exacerbate the inflammatory response in autoimmune diseases of the CNS by inducing focal BBB breakdown and migration of inflammatory cells into the lesions.
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Targeting Dipeptidyl Peptidase IV (CD26) Suppresses Autoimmune Encephalomyelitis and Up-Regulates TGF-β1 Secretion In Vivo
Andreas Steinbrecher,Dirk Reinhold,Laura Quigley,Ameer M Gado,Nancy Tresser,Leonid Izikson,Ilona Born,Jürgen Faust,Klaus Neubert,Roland Martin,Siegfried Ansorge,Stefan Brocke +11 more
TL;DR: The data suggest that DP IV inhibition represents a novel and specific therapeutic approach protecting from autoimmune disease by a mechanism that includes an active TGF-β1-mediated antiinflammatory effect at the site of pathology.
Structural abnormalities develop in the brain after ablation of the gene encoding nonmuscle myosin II-B heavy chain.
Antonella N. Tullio,Paul C. Bridgman,Nancy Tresser,Chi-Chao Chan,Mary Anne Conti,Robert S. Adelstein,Yoshinobu Hara +6 more
TL;DR: These defects may be caused by abnormalities in the cell adhesive properties of neuroepithelial cells and suggest that NMHC‐B is essential for both early and late developmental processes in the mammalian brain.
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Costimulatory markers in muscle of patients with idiopathic inflammatory myopathies and in cultured muscle cells.
Kanneboyina Nagaraju,Nina Raben,Maria L. Villalba,Carol L. Danning,Lisa Loeffler,Eunice Lee,Nancy Tresser,Andrea Abati,Patricia Fetsch,Paul H. Plotz +9 more
TL;DR: The data suggest a novel complexity in the network of cellular interactions between the infiltrated immune cells and the muscle cells in which the normal relationship between infiltrating inflammatory cells and target tissue is under a previously unrecognized set of controls.
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Study of relapsing remitting experimental allergic encephalomyelitis SJL mouse model using MION-46L enhanced in vivo MRI: early histopathological correlation.
Su Xu,E. Kay Jordan,Stefan Brocke,Jeff W.M. Bulte,Laura Quigley,Nancy Tresser,John Ostuni,Yihong Yang,Henry F. McFarland,Joseph A. Frank +9 more
TL;DR: MION‐46L enhanced MRI may be used to provide a unique sensitivity in EAE lesion detection and correlate imaging to histopathology, and eventually assist in preclinical screening of new experimental therapies directed at patients with multiple sclerosis (MS).
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