Nancy J. Reyes
Duke University
21 Papers
65 Citations
Nancy J. Reyes is an academic researcher from Duke University. The author has contributed to research in topics: T cell & Allergic conjunctivitis. The author has an hindex of 13, co-authored 21 publications. Previous affiliations of Nancy J. Reyes include Durham University & University of Texas Southwestern Medical Center.
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Papers
New insights into mononuclear phagocyte biology from the visual system
TL;DR: Novel insights in eye immune privilege are examined and recent inroads concerning retinal degeneration are discussed, both themes have been extensively studied in the visual system and show parallels with recent findings concerning mononuclear phagocytes in the central nervous system and in the periphery.
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Ocular Mucosal CD11b+ and CD103+ Mouse Dendritic Cells under Normal Conditions and in Allergic Immune Responses
Payal Khandelwal,Tomas Blanco-Mezquita,Parisa Emami,Hyun Soo Lee,Nancy J. Reyes,Rose Mathew,Randy Huang,Daniel R. Saban +7 more
TL;DR: Although CD 11b+ and CD103+ DC are both present in the normal ocular mucosa, the CD11b+ DC subset plays a dominant role in a mouse model of ocular allergy.
SYK inhibitor entospletinib prevents ocular and skin GVHD in mice
Jonathan C. Poe,Wei Jia,Julie A. Di Paolo,Nancy J. Reyes,Ji Yun Kim,Hsuan Su,John S. Sundy,Adela R. Cardones,Victor L. Perez,Benny J. Chen,Nelson J. Chao,Diana M. Cardona,Daniel R. Saban,Stefanie Sarantopoulos +13 more
TL;DR: It is found that early SYK inhibition improved blood immune cell reconstitution in GVHD mice and prolonged survival, with 60% of mice surviving to day +120 compared with 10%" of mice treated with placebo.
BAFF promotes heightened BCR responsiveness and manifestations of chronic GVHD after allogeneic stem cell transplantation.
Wei Jia,Jonathan C. Poe,Hsuan Su,Sarah Anand,Glenn K. Matsushima,Jeffrey C. Rathmell,Ivan Maillard,Vedran Radojcic,Kazuhiro Imai,Nancy J. Reyes,Diana M. Cardona,Zhiguo Li,Amy N. Suthers,Itaevia M. Curry-Chisolm,Rachel A. DiCioccio,Daniel R. Saban,Benny J. Chen,Nelson J. Chao,Stefanie Sarantopoulos +18 more
TL;DR: In this article, the authors examined B-lymphopenic μMT allo-BMT recipients and found that increased BAFF levels in cGVHD mice were not merely a reflection of B-cell number, but whether BAFF promotes disease after allogeneic bone marrow transplantation.
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Resolvin D1 treatment on goblet cell mucin and immune responses in the chronic allergic eye disease (AED) model.
Daniel R. Saban,Robin R. Hodges,Rose Mathew,Nancy J. Reyes,Chen Yu,Rebecca Kaye,William Swift,Nora Botten,Nora Botten,Nora Botten,Charles N. Serhan,Darlene A. Dartt +11 more
TL;DR: It is concluded that topical application of RvD1 reduced the ocular allergic response by local actions in conjunctival immune response and a decrease in goblet cell mucin secretion.
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