11 Papers
51 Citations
Nan Hu is an academic researcher from Soochow University (Suzhou). The author has contributed to research in topics: Tube formation & Medicine. The author has an hindex of 6, co-authored 8 publications.
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Papers
Hypoxia-pretreated ADSC-derived exosome-embedded hydrogels promote angiogenesis and accelerate diabetic wound healing.
Nan Hu,Zhengwei Cai,Xu Hong Jiang,Chuangyuan Wang,Tao Tang,Tianze Xu,Hong Chen,Xiaoqiang Li,Xiaolong Du,Wenguo Cui +9 more
TL;DR: In this article , the effects and downstream targets of hypoxic engineered exosome hydrogels in managing diabetic wound repair were explored, and it was shown that exosomes from hypoxia-pretreated ADSC-Exo (ADSC-HExo)-embedded GelMA hydrogel can accelerate diabetic wound healing via circRNA delivery.
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Upregulation of miR-483-3p contributes to endothelial progenitor cells dysfunction in deep vein thrombosis patients via SRF
Lingshang Kong,Nan Hu,Xiaolong Du,Wenbin Wang,Hong Chen,Wendong Li,Sen Wei,Hao Zhuang,Xiao-Qiang Li,Chenglong Li +9 more
TL;DR: miR-483-3p is upregulated in EPCs from DVT patients, and it targets SRF to decrease E PCs migration and tube formation and increase apoptosis in vitro, while decrease EPC's homing and thrombus resolution in vivo.
Downregulation of let-7e-5p contributes to endothelial progenitor cell dysfunction in deep vein thrombosis via targeting FASLG
Lingshang Kong,Xiaolong Du,Nan Hu,Wendong Li,Wenbin Wang,Sen Wei,Hao Zhuang,Xiao-Qiang Li,Chenglong Li +8 more
TL;DR: EPCs overexpressing let-7e-5p exhibited enhanced ability of homing and thrombus revascularization inrat model of venous thrombosis and is a potential therapeutic target in DVT treatment.
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Autophagy inhibits endothelial progenitor cells migration via the regulation of MMP2, MMP9 and uPA under normoxia condition
TL;DR: It is demonstrated that autophagy could regulate the EPCs migration through mTOR-P70 S6K pathway, and MMP2, MMP9 and uPA may also involve in the regulation mechanism.
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Metformin regulates differentiation of bone marrow-derived endothelial progenitor cells via multiple mechanisms
TL;DR: The results here showed that metformin could regulate the differentiation of EPCs and autophagy related pathway and AMPK-eNOS-NO pathway were involved in the mechanisms.
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