Nam Tran
Yale University
8 Papers
112 Citations
Nam Tran is an academic researcher from Yale University. The author has contributed to research in topics: Knowledge representation and reasoning & Ontology (information science). The author has an hindex of 6, co-authored 8 publications.
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Papers
Integrative Analysis of Epigenetic Modulation in Melanoma Cell Response to Decitabine: Clinical Implications
Ruth Halaban,Michael Krauthammer,Mattia Pelizzola,Elaine Cheng,Daniela Kovacs,Mario Sznol,Stephan Ariyan,Deepak Narayan,Antonella Bacchiocchi,Annette M. Molinaro,Yuval Kluger,Min Deng,Nam Tran,Wengeng Zhang,Mauro Picardo,Jan J. Enghild +15 more
TL;DR: Improved therapy can be achieved by comprehensive analysis of cancer cells, identified biomarkers for patient's selection and monitoring response, as well as targets for improved combination therapy.
Hypothesizing about Signaling Networks
Nam Tran,Chitta Baral +1 more
TL;DR: It is shown that the hypothesis formation problem can be translated into an abduction problem and this translation facilitates the complexity analysis and an efficient implementation of the proposed action language based framework for hypothesis formation for signaling networks.
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Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma
TL;DR: It is shown that the combination of promoter CpG content and methylation level informs the ability of decitabine treatment to up-regulate gene expression, and a classifier is built to predict gene up-regulation based on promoter methylation and C pG content, which achieves a performance of 0.77 AUC.
Reasoning about non-immediate triggers in biological networks
Nam Tran,Chitta Baral +1 more
TL;DR: An action language is proposed that allows for refinements of biological knowledge, although at a higher cost in terms of complexity.
•Proceedings Article
Enriching PubMed Related Article Search with Sentence Level Co-citations
Nam Tran,Pedro Alves,Shuangge Ma,Michael Krauthammer +3 more
- 14 Nov 2009
TL;DR: This paper proposes to enrich PubMed with a new type of related article link based on citations within a single sentence (i.e. sentence level co-citations or SLCs), and demonstrates that articles linked by S LCs are highly related.
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