Nadine Tung
Beth Israel Deaconess Medical Center
318 Papers
1.2K Citations
Nadine Tung is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 73, co-authored 266 publications. Previous affiliations of Nadine Tung include Beth Israel Deaconess Hospital & Creighton University.
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Papers
Evolutionary Pathways in BRCA1-Associated Breast Tumors
Filipe C. Martins,Subhajyoti De,Subhajyoti De,Vanessa Almendro,Vanessa Almendro,Mithat Gonen,So Yeon Park,Joanne L. Blum,William Herlihy,Gabrielle Ethington,Stuart J. Schnitt,Nadine Tung,Judy Garber,Katharina Fetten,Franziska Michor,Kornelia Polyak +15 more
TL;DR: Although there is no obligatory order of events, it is found that loss of PTEN is the most common first event and is associated with basal-like subtype, whereas in the majority of luminal tumors, mutation of TP53 occurs first and mutant PIK3CA is rarely detected.
Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers
Joanne Kotsopoulos,Jan Lubinski,Leonardo Salmena,Henry T. Lynch,Charmaine Kim-Sing,William D. Foulkes,Parviz Ghadirian,Susan L. Neuhausen,Rochelle Demsky,Nadine Tung,Peter Ainsworth,Leigha Senter,Andrea Eisen,Charis Eng,Christian F. Singer,Ophira Ginsburg,Ophira Ginsburg,Joanne L. Blum,Tomasz Huzarski,Aletta Poll,Ping Sun,Steven A. Narod +21 more
TL;DR: Analysis of breastfeeding and risk of breast cancer using a large matched sample of BRCA mutation carriers extends the previous findings that breastfeeding protects against BRCa1-, but not BRC a2-associated breast cancer.
Effect of Oophorectomy on Survival After Breast Cancer in BRCA1 and BRCA2 Mutation Carriers
Kelly A. Metcalfe,Kelly A. Metcalfe,Henry T. Lynch,William D. Foulkes,Nadine Tung,Charmaine Kim-Sing,Olufunmilayo I. Olopade,Andrea Eisen,Barry P. Rosen,Carrie Snyder,Shelley Gershman,Shelley Gershman,Ping Sun,Steven A. Narod +13 more
TL;DR: Oophorectomy is associated with a decrease in mortality in women with breast cancer and a BRCA1 mutation, and women with estrogen receptor-negative breast cancerand a BRA1 mutation should undergo oophoreCTomy shortly after diagnosis.
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Disruption of the expected positive correlation between breast tumor size and lymph node status in BRCA1-related breast carcinoma
William D. Foulkes,Kelly A. Metcalfe,Wedad Hanna,Henry T. Lynch,Parviz Ghadirian,Nadine Tung,O. I. Olopade,Barbara L. Weber,Jane McLennan,Ivo A. Olivotto,Ping Sun,Pierre O. Chappuis,Louis R. Bégin,Jean Sébastien Brunet,Jean Sébastien Brunet,Steven A. Narod +15 more
TL;DR: The authors questioned whether the known positive correlation between tumor size and lymph node status also was present in women with BRCA1‐related breast carcinomas.
121
Family History of Cancer and Cancer Risks in Women with BRCA1 or BRCA2 Mutations
Kelly A. Metcalfe,Jan Lubinski,Henry T. Lynch,Parviz Ghadirian,William D. Foulkes,Charmaine Kim-Sing,Susan L. Neuhausen,Nadine Tung,Barry P. Rosen,Jacek Gronwald,Peter Ainsworth,Kevin Sweet,Andrea Eisen,Ping Sun,Steven A. Narod +14 more
TL;DR: Cancer incidence rates for a multinational cohort comprising 3011 women with BRCA1 or BRCa2 mutations who were followed up for a mean of 3.9 years, during which time 243 incident breast or ovarian cancers were recorded.
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