Nader Hussein
Lebanese University
21 Papers
61 Citations
Nader Hussein is an academic researcher from Lebanese University. The author has contributed to research in topics: Downregulation and upregulation & Cancer research. The author has an hindex of 10, co-authored 16 publications. Previous affiliations of Nader Hussein include Claude Bernard University Lyon 1.
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Papers
Circulating miR-150 and miR-342 in plasma are novel potential biomarkers for acute myeloid leukemia
Hussein Fayyad-Kazan,Nizar Bitar,Mehdi Najar,Philippe Lewalle,Mohammad Fayyad-Kazan,Rabih Badran,Eva Hamade,Ahmad Daher,Nader Hussein,Rim ElDirani,Fadwa Berri,Luc Vanhamme,Arsène Burny,Philippe Martiat,Redouane Rouas,Bassam Badran +15 more
TL;DR: QRT-PCR results showed that the expression level of these two miRs in complete remission AML patients resembled that of healthy controls, indicating the additive effect in the diagnostic value of these 2 miRNAs.
JMJD6 regulates ERα methylation on arginine.
TL;DR: In this article, the authors showed that JMJD6, the only arginine demethylase described so far, interacts with and regulates methylated ERα (metERα) function.
Downregulation of microRNA-24 and -181 parallels the upregulation of IFN-γ secreted by activated human CD4 lymphocytes
Hussein Fayyad-Kazan,Eva Hamade,Redouane Rouas,Mehdi Najar,Mohammad Fayyad-Kazan,Nabil El Zein,Rim ElDirani,Nader Hussein,Maya Fakhry,Carine Al-Akoum,Arsène Burny,Philippe Martiat,Bassam Badran +12 more
TL;DR: Identifying target sites for miR-24 and miR -181 in IFN-γ-3'UTR points to a novel regulatory mechanism of this crucial gene.
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LKB1 regulates PRMT5 activity in breast cancer
Hanine Lattouf,Loay Kassem,Julien Jacquemetton,Julien Jacquemetton,Julien Jacquemetton,Ali Choucair,Ali Choucair,Ali Choucair,Coralie Poulard,Olivier Tredan,Laura Corbo,Laura Corbo,Laura Corbo,Mona Diab-Assaf,Nader Hussein,Isabelle Treilleux,Muriel Le Romancer,Muriel Le Romancer,Muriel Le Romancer +18 more
TL;DR: Analyzing its expression in a large cohort of breast cancer patients revealed higher nuclear PRMT5 levels in ERα‐positive tumors and an association with prolonged disease free and overall survival, and identified T132, 139 and 144 residues, located in the TIM‐Barrel domain ofPRMT5, as target sites for LKB1 phosphorylation.
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Reconstituted expression of menin in Men1-deficient mouse Leydig tumour cells induces cell cycle arrest and apoptosis
Nader Hussein,Huguette Casse,Sandra Fontanière,Anne-Marie Morera,Marie J. Asensio,Skander Bakeli,Jie L. Lu,Isabelle Coste,Nathalie di Clemente,Philippe Bertolino,Chang X. Zhang +10 more
TL;DR: The importance of menin expression in cell cycle and cell survival control in endocrine cells is highlighted, and insights into the mechanisms of tumour suppression by menin in related endocrine tumours are provided.
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