5 Papers
Na Li is an academic researcher from Chinese Center for Disease Control and Prevention. The author has contributed to research in topics: Mycobacterium tuberculosis & Immunogenicity. The author has an hindex of 1, co-authored 2 publications.
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Papers
Immunological Evaluation of a Novel Mycobacterium tuberculosis Antigen Rv0674
Tong Yang Xiao,Hai Can Liu,Xiaoqin Li,Ming Xiang Huang,Gui Lian Li,Na Li,Yu Han Yan,Qiao Luo,Xue Zhi Wang,Ma Chao Li,Kang Lin Wan +10 more
TL;DR: Rv0674 may be a good potential candidate for the development of TB serological diagnosis and a new TB vaccine, and was characterized as a Th1/Th2-mixed-type protective immunity with the predominance of Th1 cytokines.
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High Immunogenicity of a T-Cell Epitope-Rich Recombinant Protein Rv1566c-444 From Mycobacterium tuberculosis in Immunized BALB/c Mice, Despite Its Low Diagnostic Sensitivity
Xiuli Luan,Xue Ting Fan,Ruihuan Wang,Yun Deng,Zi-Xuan Chen,Na Li,Yu Han Yan,Xiaoyan Li,Haican Liu,Guilian Li,Kanglin Wan +10 more
TL;DR: The results showed the potential of the recombinant protein Rv1566c-444 enriched with T-Cell epitopes from Rv 1566c as a host T cell response measuring biomarker for TB diagnosis and support further evaluation of Rvteen66c -444 as vaccine antigen against MTB challenge in animal models in the form of protein mixture or fusion protein.
Immunogenicity of Whole Mycobacterium intracellulare Proteins and Fingding on the Cross-Reactive Proteins between M. intracellulare and M. tuberculosis.
Shi Qi Xiao,Da Xu,Hong Yang Duan,Xue Ting Fan,Gui Lian Li,Wen Zhang,Ma Chao Li,Na Han,Xin Yao Li,Na Li,Li Lan Zhao,Xiu Qin Zhao,Kang Lin Wan,Hai Can Liu,Wen Hai Feng +14 more
TL;DR: In this article, the authors evaluated the immunogenicity of Mycobacterium intracellulare proteins and determined the cross-reactive proteins between M. intracellular and M. tuberculosis.
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Omics analysis of Mycobacterium tuberculosis isolates uncovers Rv3094c, an ethionamide metabolism-associated gene
Li Wan,Peilei Hu,Lili Zhang,Zhao-Xi Wang,Joy Fleming,Bo Ni,Jianjun Luo,Cha-Xiang Guan,Liqiong Bai,Yunhong Tan,Haican Liu,Na Li,Tongyang Xiao,Hua Bai,Yong-An Zhang,Xian-En Zhang,Kanglin Wan,Lijun Bi,Songying Ouyang,Hongtai Zhang +19 more
TL;DR: In this paper , the authors identify 388 genes with lineage-related differential expression and 68 candidate drug resistance-associated gene pairs/clusters in 11 M. tuberculosis isolates (variable lineage/drug resistance profiles).
Exploring the immunogenicity of Rv2201-519: A T-cell epitope-based antigen derived from Mycobacterium tuberculosis AsnB with implications for tuberculosis infection detection and vaccine development.
Xiuli Luan,Xue Ting Fan,Guilian Li,Mchao Li,Na Li,Yuhan Yan,Xiuqin Zhao,Haican Liu,Kanglin Wan +8 more
TL;DR: The current evidence suggests that Rv2201-519 could potentially serve as an immunodominant protein for tuberculosis infection screening, laying the groundwork for further evaluation in recombinant Bacillus Calmette-Guérin (BCG) and subunit vaccines against MTB challenges in future studies.