N. Tim Cable
University of Birmingham
19 Papers
169 Citations
N. Tim Cable is an academic researcher from University of Birmingham. The author has contributed to research in topics: Colorectal cancer & Aerobic exercise. The author has an hindex of 12, co-authored 19 publications. Previous affiliations of N. Tim Cable include Aspire Academy & Liverpool John Moores University.
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Papers
Acute β-Adrenergic Overload Produces Myocyte Damage through Calcium Leakage from the Ryanodine Receptor 2 but Spares Cardiac Stem Cells
Georgina M. Ellison,Georgina M. Ellison,Daniele Torella,Daniele Torella,Ioannis Karakikes,Saranya Purushothaman,Antonio Curcio,Cosimo Gasparri,Ciro Indolfi,N. Tim Cable,David F. Goldspink,Bernardo Nadal-Ginard,Bernardo Nadal-Ginard +12 more
TL;DR: A single injection of ISO causes diffuse myocyte death through Ca2+ leakage secondary to the acutely dysfunctional RyR2, and CSCs are resistant to the noxious effects of an acute hyperadrenergic state and through their activation participate in the response to the ISO-induced myocardial injury.
169
Physical activity before and after diagnosis of colorectal cancer : disease risk, clinical outcomes, response pathways and biomarkers
TL;DR: There is some evidence that improvements in cardiorespiratory fitness reduce adverse effects from cancer treatment when physical activity is undertaken following diagnosis of colorectal cancer, and there is little available evidence for the benefits of physical activity before diagnosis of colon cancer for disease-specific survival and prognosis.
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The effect of 48 weeks of aerobic exercise training on cutaneous vasodilator function in post-menopausal females.
Gary J. Hodges,Gary J. Hodges,Lisa Sharp,Claire Stephenson,Ashish Patwala,Keith George,David F. Goldspink,N. Tim Cable +7 more
TL;DR: Aerobic exercise produces positive adaptations in the cutaneous vasodilator function to local heating as well as in cutaneous endothelial and endothelial-independent vasODilator mechanisms.
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Point:Counterpoint: Exercise training does/does not induce vascular adaptations beyond the active muscle beds
TL;DR: A few years ago the authors published a series of studies that investigated the impact of exercise training on vascular function in humans, finding that a combination of resistance and aerobic exercise involved a similar exercise training intervention.
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Endurance exercise training enhances cutaneous microvascular reactivity in post-menopausal women
TL;DR: Cutaneous microvascular reactivity is reduced in post-menopausal women compared to young controls and increased to similar levels after 24-36 weeks of mild-to-moderate endurance exercise.
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