N N Spirin
Yaroslavl State University
15 Papers
16 Citations
N N Spirin is an academic researcher from Yaroslavl State University. The author has contributed to research in topics: Multiple sclerosis & Coronavirus. The author has an hindex of 3, co-authored 13 publications.
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Papers
[Primary-progressive multiple sclerosis in Russia: a medical-sociological study involving patients and neurologists].
Ya. V. Vlasov,M. V. Churakov,M. A. Kurapov,T. N. Gromova,Ekaterina Popova,O. V. Boyko,N N Spirin,S A Sivertseva,G N Belskaya,N A Malkova,F A Habirov,T. I. Haybullin,Kotov Sv,I. V. Greshnova,E. I. Ivashinenkova,M. A. Bakalova,I. A. Yampolskaya-gosteva,A N Boyko +17 more
TL;DR: The study revealed typical medical and social problems patients with PPMS faced and a significant decrease in quality-of-life of PPMS patients was shown.
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Homocysteine and markers of endothelial dysfunction in multiple sclerosis
TL;DR: In this paper, the authors identify hyperhomocysteinemia and assess its possible association with the course and other markers of endothelial damage in multiple sclerosis, and find that more than half of patients with MS had hyper-homocysteemia, and a significantly higher homocysteine level was found in male patients than women.
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Nervous system damage in COVID-19 with an emphasis on the management of patients with multiple sclerosis
TL;DR: The paper gives the data available in the literature on nervous system damage and the characteristics of clinical and magnetic resonance imaging manifestations of brain damage in COVID-19, a pandemic coronavirus that targets the lung with the development of acute respiratory failure.
New directions of immunocorrection in multiple sclerosis
A N Boyko,Khachanova Nv,M V Melnikov,S A Sivertseva,E. P. Evdoshenko,N N Spirin,A. V. Vasilyev,O. L. Rozenson +7 more
TL;DR: It is noted that immunoreconstitution therapy has advantages over immunomodulation and immunosuppression maintenance therapy for some patients, and is assumed that patients with a high risk of multiple sclerosis progression are the optimal group of patients for the early use of selective immunore Constitution therapy.
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Polymorphic variants of the immune response genes as risk factors for primary progressive multiple sclerosis
Ekaterina Popova,Ivan Kiselev,A N Boyko,S A Sivertseva,N A Malkova,D. S. Korobko,N N Spirin,D. S. Kasatkin,A. V. Karaeva,E L Turova,N N Spirina,L I Volkova,Natalia Baulina,V. V. Bashinskaya,Olga Kulakova,O O Favorova +15 more
TL;DR: The genotypes of IL-4 (rs2243250)*C/C and CLEC16A (rs6498169)*G/G were associated with PPMS in Russians and the association between the HLA-DRB1*15 and PPMS found out in other populations was confirmed in Russians.
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