N. Ishikawa
Hokkaido University
24 Papers
312 Citations
N. Ishikawa is an academic researcher from Hokkaido University. The author has contributed to research in topics: Monoclonal antibody & Antigen. The author has an hindex of 10, co-authored 24 publications. Previous affiliations of N. Ishikawa include Kitasato University.
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Papers
Serologic dissection of HLA-D specificities by the use of monoclonal antibodies
Masanori Kasahara,T Takenouchi,Kazumasa Ogasawara,Hitoshi Ikeda,T. Okuyama,N. Ishikawa,Junko Moriuchi,Akemi Wakisaka,Yuko Kikuchi,Miki Aizawa,Takehisa Kaneko,Noboru Kashiwagi,Y. Nishimura,Takehiko Sasazuki +13 more
TL;DR: This is the first clearcut serologic identification of these three HLA-DR4-associated Hla-D specificities, which have been indistinguishable by conventional serology and identified only by cellular techniques.
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Serologic dissection of HLA-D specificities by the use of monoclonal antibodies. II. Distinction between HLA-Dw2 and HLA-Dw12.
Masanori Kasahara,T Takenouchi,Hitoshi Ikeda,Kazumasa Ogasawara,T. Okuyama,N. Ishikawa,Akemi Wakisaka,Yuko Kikuchi,Miki Aizawa +8 more
TL;DR: The data suggest that the two kinds of HLA-DR2-positive homozygous typing cell lines with distinct H LA-D specificity can be distinguished from each other by using solely serologic methods.
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Detection of a novel HLA-DQ specificity: serological and immunochemical analyses by a monoclonal antibody.
N. Ishikawa,Hiroshi Kojima,Tsuguyo Nakayama,Hiroshi Kunikane,S. Hawkin,Yuichiro Fukasawa,Hitoshi Ikeda,Kazumasa Ogasawara,Masanori Kasahara,Yasutaka Tajima,Yukio Kakuta,Akemi Wakisaka,Miki Aizawa +12 more
TL;DR: Two-dimensional gel analyses indicated that the mAb recognized class II antigens which were encoded by the HLA-DQ locus, and in genetic analysis, the gene encoding the class II antigen detected by HU-46 met the Hardy-Weinberg condition as a fourth allele of the D Q locus.
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A monoclonal antibody that detects a polymorphic determinant common to HLA-DR1 and 2.
Masanori Kasahara,Kazumasa Ogasawara,Hitoshi Ikeda,T. Okuyama,N. Ishikawa,T Takenouchi,Akemi Wakisaka,Yuko Kikuchi,Miki Aizawa +8 more
TL;DR: HU-30 appears to be of great value as a tissue typing reagent monospecific for HLA-DR2, with much stronger cytotoxic activity against HLA -DR2 positive B cell lines.
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Evidence for polymorphism of MB3 antigens among three HLA-D clusters associated with HLA-DR4.
Hitoshi Ikeda,Masanori Kasahara,Kazumasa Ogasawara,T Takenouchi,T. Okuyama,N. Ishikawa,Akemi Wakisaka,Yuko Kikuchi,Miki Aizawa +8 more
TL;DR: The results of sequential coprecipitation assays and two-dimensional gel analyses showed that both H U-18 and HU-23 recognize antigenic determinants borne on M133 but not on HLA-DRw6, suggesting the existence of polymorphism in MB3 antigens.
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