N Fatemi
Royan Institute
22 Papers
4 Citations
N Fatemi is an academic researcher from Royan Institute. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 4, co-authored 7 publications.
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Papers
DNA methylation biomarkers in colorectal cancer: Clinical applications for precision medicine
N Fatemi,Sascha Tierling,Hamidreza Aboulkheyr Es,Maryam Varkiani,Ehsan Nazemalhosseini Mojarad,Hamid Asadzadeh Aghdaei,Jörn Walter,Mehdi Totonchi +7 more
TL;DR: The need to further identify and stratify methylation‐biomarkers and to develop robust and effective detection methods that are applicable for a routine clinical setting of CRC diagnostics particularly at the early stage of the disease is emphasized.
Effect of tertiary-butyl hydroperoxide (TBHP)-induced oxidative stress on mice sperm quality and testis histopathology.
N Fatemi,Mohammad Hossein Sanati,M. Jamali Zavarehei,Hoda Ayat,Vahid Esmaeili,A. Golkar-Narenji,M. Zarabi,Hamid Gourabi +7 more
TL;DR: Exposure to tertiary‐butyl hydroperoxide‐induced oxidative stress caused a decrease in sperm parameters and testis cells viability, due to an increase level of ROS in the testis and their deleterious effects on genomic levels.
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Principles of Molecular Utility for CMS Classification in Colorectal Cancer Management
Leili Rejali,Fatemeh Sanjabi,N Fatemi,Hamid Asadzadeh Aghdaei,Mahsa Saeedi Niasar,Pardis Ketabi Moghadam,Ehsan Nazemalhosseini Mojarad,Enrico Mini,Stefania Nobili +8 more
TL;DR: In this article , the authors contextualized the consensus molecular subtype (CMS) classification in different settings, discussing its relationships with precursor lesions, tumor immunophenotype, and gut microbiota, as well as its role in predicting prognosis and/or response to pharmacological treatments, as a crucial step towards precision medicine.
•Journal Article
Optimization of The Electroporation Conditions for Transfection of Human Factor IX into The Goat Fetal Fibroblasts.
Amir Amiri Yekta,A Dalman,Mohammad Hossein Sanati,N Fatemi,Hamed Vazirinasab,Alireza Zomorodipour,Mohammad Chehrazi,Hamid Gourabi +7 more
TL;DR: The results showed an increase in DNA concentration could affect an exponential surge in the electroporation efficiency, and increasing amount of using the vector 40µg/pulse efficiently increased the number of transfected cells.
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Whole exome sequencing identifies MAP3K1, MSH2, and MLH1 as potential cancer-predisposing genes in familial early-onset colorectal cancer.
N Fatemi,Siang Jyun Tu,Chin-Chun Chung,Pardis Ketabi Moghadam,Ehsan Nazemalhosseini Mojarad,Amin Sadeghi,Mehdi Totonchi,Hamid Asadzadeh Aghdaei,Jan-Gowth Chang +8 more
TL;DR: Wang et al. as discussed by the authors applied WES in five early-onset colorectal cancer (CRC) patients from three unrelated families to identify novel genetic variants that could be linked to rapid disease development.
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