Murielle Saade
Spanish National Research Council
20 Papers
67 Citations
Murielle Saade is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Neurogenesis & Centrosome. The author has an hindex of 9, co-authored 15 publications. Previous affiliations of Murielle Saade include French Institute of Health and Medical Research.
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Papers
Shh-mediated centrosomal recruitment of PKA promotes symmetric proliferative neuroepithelial cell division
TL;DR: By controlling centrosomal protein assembly, it is proposed that Shh signalling overcomes the intrinsic asymmetry at the centrosome during neuroepithelial cell division, thereby promoting self-expanding symmetric divisions and the expansion of the progenitor pool.
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A centrosomal view of CNS growth.
TL;DR: The multiple roles played by centrosomes during embryonic growth of the vertebrate central nervous system are discussed, highlighting the links between centrosome dysfunction and microcephaly.
Dynamic distribution of Spatial during mouse spermatogenesis and its interaction with the kinesin KIF17b.
Murielle Saade,Magali Irla,Magali Irla,Jérôme Govin,Geneviève Victorero,Geneviève Victorero,Michel Samson,Catherine Nguyen,Catherine Nguyen +8 more
TL;DR: Findings imply a function of Spatial in spermatid differentiation as a new cargo of kinesin KIF17b, in a microtubule-dependent mechanism specific to the manchette and the principal piece of the sperm tail.
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A General Survey of Thymocyte Differentiation by Transcriptional Analysis of Knockout Mouse Models
Denis Puthier,Florence Joly,Magali Irla,Murielle Saade,Geneviève Victorero,Béatrice Loriod,Catherine Nguyen +6 more
TL;DR: This study used microarray technology to extensively describe transcriptional events regulating αβ T cell fate and provides the first evidence that such an approach may also highlight the complex cross-talk events that occur between maturing T cells and stroma.
Multimerization of Zika Virus-NS5 Causes Ciliopathy and Forces Premature Neurogenesis
Murielle Saade,Diego S. Ferrero,José Blanco-Ameijeiras,Elena Gonzalez-Gobartt,Marco Flores-Mendez,Marco Flores-Mendez,Victor M. Ruiz-Arroyo,Elena Martínez-Sáez,Santiago Ramón y Cajal,Naiara Akizu,Naiara Akizu,Núria Verdaguer,Elisa Martí +12 more
TL;DR: It is shown that the ZikV-NS5 protein interacts with host proteins at the base of the primary cilia in neural progenitor cells, causing an atypical non-genetic ciliopathy and premature neuron delamination.
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