Munju Cho
Inje University
18 Papers
202 Citations
Munju Cho is an academic researcher from Inje University. The author has contributed to research in topics: Wnt signaling pathway & Catenin. The author has an hindex of 13, co-authored 18 publications.
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Papers
Protein-kinase-C-mediated β-catenin phosphorylation negatively regulates the Wnt/β-catenin pathway
Jungsug Gwak,Munju Cho,Soo-Jung Gong,Jaejoon Won,Dong-Eun Kim,Eun Young Kim,Sang Sup Lee,Mina Kim,Tae Kook Kim,Jae-Gook Shin,Sangtaek Oh +10 more
TL;DR: Small-molecule-based identification of protein kinase C (PKC)-mediated β-catenin phosphorylation as a novel mechanism regulating the Wnt/β- catenin pathway is presented and it is suggested that the PKC pathway negatively regulates the β-Catenin level outside of the Wnnt/ β-catsin pathway.
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Cardamonin suppresses melanogenesis by inhibition of Wnt/β-catenin signaling
Munju Cho,Min-Jung Ryu,Yongsu Jeong,Young-Hwa Chung,Dong-Eun Kim,Ho-Song Cho,Sang-Jin Kang,Jong-Sub Han,Min-Youl Chang,Cheon-Koo Lee,Mu-Hyun Jin,Ho-Jeoung Kim,Sangtaek Oh +12 more
TL;DR: Cardamonin significantly suppressed the expression of microphthalmia-associated transcription factor and tyrosinase in human normal melanocytes, thereby decreasing intracellular melanin production and indicating that cardamonin may be a potential whitening agent for use in cosmetics and in the medical treatment of hyperpigmentation disorders.
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Diclofenac attenuates Wnt/β‐catenin signaling in colon cancer cells by activation of NF‐κB
Munju Cho,Jungsug Gwak,Seoyoung Park,Jaejoon Won,Dong-Eun Kim,Sung Su Yea,In-June Cha,Tae Kook Kim,Jae-Gook Shin,Sangtaek Oh +9 more
TL;DR: Diclofenac inhibits Wnt/β‐catenin signaling via the activation of NF‐κB in colon cancer cells and reduces the expression of β‐ catenin/TCF‐dependent genes.
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Murrayafoline A attenuates the Wnt/β-catenin pathway by promoting the degradation of intracellular β-catenin proteins
Hyuk Choi,Jungsug Gwak,Munju Cho,Min-Jung Ryu,Jee Hyun Lee,Sang Kyum Kim,Young Ho Kim,Gye-Won Lee,Mi-Young Yun,Nguyen Manh Cuong,Jae-Gook Shin,Gyu-Yong Song,Sangtaek Oh +12 more
TL;DR: Murrayafoline A, a carbazole alkaloid isolated from Glycosmis stenocarpa, antagonized CRT that was stimulated by Wnt3a-conditioned medium or LiCl, and repressed the expression of cyclin D1 and c-myc, which is known beta-catenin/T cell factor (TCF)-dependent genes and thus inhibited the proliferation of various colon cancer cells.
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