Mukesh Kumar
Central Drug Research Institute
4 Papers
57 Citations
Mukesh Kumar is an academic researcher from Central Drug Research Institute. The author has contributed to research in topics: Micelle & Pharmacokinetics. The author has an hindex of 3, co-authored 4 publications.
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Papers
L-Proline catalysed multicomponent synthesis of 3-amino alkylated indolesvia a Mannich-type reaction under solvent-free conditions
TL;DR: In this article, an efficient L-proline catalyzed one-pot synthesis of 3-amino-alkylated indoles has been developed via a three-component Mannich-type reaction viz. secondary amines, aldehyde and indoles under solvent-free conditions at room temperature.
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Micelle promoted multicomponent synthesis of 3-amino alkylated indoles via a Mannich-type reaction in water
TL;DR: An efficient micelle promoted one-pot synthesis of 3-amino alkylated indoles has been developed via a three-component Mannich-type reaction from secondary amines, aldehydes and indoles in water under mild reaction conditions.
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Simultaneous determination of fluconazole and ofloxacin in rabbit tear fluid by LC-MS/MS: Application to ocular pharmacokinetic studies.
Boymatova Dilnoza Axmadovna,Sachin Nashik Sanap,Anjali Mishra,Amol Chhatrapati Bisen,Sristi Agrawal,Arpon Biswas,Sarvesh Kumar Verma,Mukesh Kumar,Rabi Sankar Bhatta +8 more
TL;DR: In this article, a responsive, selective, and fast method for estimation of fluconazole and ofloxacin in rabbit tears using high-performance liquid chromatography together with tandem mass spectrometry (LC-MS/MS) was established and validated using ketoconazole as an internal standard (IS).
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Metal-free C(sp3)–H bond activation: first synthesis of diaryl-pyridinium-azaarene-butenolate zwitterionic salts on chalcones
TL;DR: An efficient route for the synthesis of diaryl-pyridinium-azaarene-butenolate zwitterionic derivatives via metal-free, iodine-mediated C(sp3)–H bond activation of alkyl-azaarnes on addition to the α,β-unsaturated carbonyls has been reported.
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