Mu Li
Life Technologies
13 Papers
68 Citations
Mu Li is an academic researcher from Life Technologies. The author has contributed to research in topics: Exosome & Microvesicles. The author has an hindex of 8, co-authored 13 publications.
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Papers
Control of Cholesterol Metabolism and Plasma High-Density Lipoprotein Levels by microRNA-144
Cristina M. Ramírez,Noemi Rotllan,Alexander V. Vlassov,Alexander V. Vlassov,Alberto Dávalos,Mu Li,Leigh Goedeke,Juan F. Aranda,Daniel Cirera-Salinas,Elisa Araldi,Alessandro Salerno,Amarylis C. B. A. Wanschel,Jiri Zavadil,Antonio Castrillo,Antonio Castrillo,Jungsu Kim,Yajaira Suárez,Carlos Fernández-Hernando +17 more
TL;DR: In this paper, the miRNA expression signature of macrophages stimulated with LXR agonists was mapped to miRNA profiling microarray analysis in primary mouse peritoneal macrophage and mouse livers.
Methods for the extraction and RNA profiling of exosomes
Emily Zeringer,Mu Li,Tim Barta,Jeoffrey Schageman,Ketil W. Pedersen,Axl Neurauter,Susan Magdaleno,Robert Setterquist,Alexander V. Vlassov +8 more
TL;DR: A set of reagents and a workflow allowing fast and efficient extraction of exosomes, followed by isolation of RNA and its analysis by qRT-PCR and other techniques are successfully developed.
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Stem-Loop RT-PCR Quantification of siRNAs In Vitro and In Vivo
Angie Cheng,Mu Li,Yu Liang,Yu Wang,Linda Wong,Caifu Chen,Alexander V. Vlassov,Susan Magdaleno +7 more
TL;DR: Applied Biosystems TaqMan-based stem-loop RT-PCR technology is leveraged to enable robust quantification of siRNA, including chemically modified siRNA molecules, in vitro and in vivo.
52
Patent
Methods and compositions for exosome isolation
Alexander V. Vlassov,Mu Li,Emily Zeringer,Richard Conrad +3 more
- 24 Oct 2014
TL;DR: In this paper, methods, compositions and kits for the isolation of exosomes from biological fluids and tissues are described, where volume-excluding polymers are used to precipitate exosome from biological samples, thereby allowing exosomal isolation by low-speed (benchtop) centrifugation or filtration.
35
Direct Isolation of Exosomes from Cell Culture: Simplifying Methods for Exosome Enrichment and Analysis
Ketil W. Pedersen,Bente Kierulf,Ingrid Manger,Morten P. Oksvold,Mu Li,Alex,er Vv,Norbert Roos,Anette Kullmann,Axl Neurauter +9 more
TL;DR: In this article, a direct method for specific isolation of exosomes from cell culture supernatant suitable for a range of different downstream applications was established, which can be used for early detection of disease, monitoring of disease and/or effect of treatment.