Moshira A. El Deeb
Al-Azhar University
8 Papers
5 Citations
Moshira A. El Deeb is an academic researcher from Al-Azhar University. The author has contributed to research in topics: Chemistry & Cell cycle. The author has an hindex of 2, co-authored 4 publications.
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Papers
Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
Mohamed Hagras,Moshira A. El Deeb,Heba S.A. El-Zahabi,Eslam B. Elkaeed,Ahmed B.M. Mehany,Ibrahim H. Eissa +5 more
TL;DR: In this paper, the authors proposed a new anticancer agents with potential activity against tubulin polymerisation. But, they did not consider the effect of colchicine binding site inhibitors.
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Potential antiviral and anticancer effect of imidazoles and bridgehead imidazoles generated by HPV-Induced cervical carcinomas via reactivating the P53/ pRb pathway and inhibition of CA IX
TL;DR: In this article, a simple and green solvent-free protocol was applied for the synthesis of novel imidazoles and bridgehead imidaze (purine analogs) via versatile straightforward synthetic routes.
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Annelation of substituted 3-Hydrazinylimidazo [2,1-c] [1,2,4]triazolone to a series of fused [1,2,4]triazepine and [1,2,4]triazine analogues and evaluation of their anticancer activity
TL;DR: In this article, a series of annelated triazole derivatives were synthesized from the reactive binucleophile 3-hydrazinyl-5-(4-methoxybenzylidene)-7-phenyl-5H-imidazo.
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Imidazo[1,2,4]triazolone and Fused Imidazo[1,2,4]triazolone Derivatives: Synthesis, In Vitro Anticancer screening, CDK2 inhibitory activity, and Molecular modelling studies
TL;DR: In this article , the synthesis of new substituted and fused imidazotriazole derivatives via different addition and cyclocondensation pathways was reported, which showed high activity against leukemia K-562 (51.00%), RPMI-8226 (68.36%) and breast cancer MCF-7 (56.76%) cell lines.
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New thiouracil derivatives as histone deacetylase inhibitors and apoptosis inducers: design, synthesis and anticancer evaluation.
Omnia R. Elbatrawy,Moshira A. El Deeb,Mohamed Hagras,F. Agili,Maghawry Hegazy,Ahmed A. El-Husseiny,Mohamed Amr Elkady,Ibrahim H. Eissa,Samar A. El-Kalyoubi +8 more
TL;DR: Compound 7e has a promising anticancer activity targeting HDAC, and shows the highest antiproliferative effects against MCF7, HepG2 and HCT116 cell lines.
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