Morten J. Buch-Pedersen
National Research Foundation of South Africa
26 Papers
369 Citations
Morten J. Buch-Pedersen is an academic researcher from National Research Foundation of South Africa. The author has contributed to research in topics: ATPase & Proton pump. The author has an hindex of 17, co-authored 26 publications. Previous affiliations of Morten J. Buch-Pedersen include University of Copenhagen.
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Papers
A structural overview of the plasma membrane Na + ,K + -ATPase and H + -ATPase ion pumps
J. Preben Morth,Bjørn Panyella Pedersen,Bjørn Panyella Pedersen,Bjørn Panyella Pedersen,Morten J. Buch-Pedersen,Morten J. Buch-Pedersen,Jens Peter Andersen,Jens Peter Andersen,Bente Vilsen,Bente Vilsen,Michael G. Palmgren,Michael G. Palmgren,Poul Nissen,Poul Nissen +13 more
TL;DR: Structural information provides insight into the function of these two distinct but related P-type pumps, which maintain a proton gradient in plants and fungi and a Na+ and K+ gradient in animal cells.
398
Crystal structure of a plasma membrane proton pump
TL;DR: In this article, the crystal structure of a plasma membrane proton pump type ATPase was used for identification of modulators of ATPases as well as uses of such modulators.
298
The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm.
Anne-Marie Lund Winther,Maike Bublitz,Maike Bublitz,Jesper Lykkegaard Karlsen,Jesper Lykkegaard Karlsen,Jesper V. Møller,Jesper V. Møller,John Bondo Hansen,Poul Nissen,Poul Nissen,Morten J. Buch-Pedersen +10 more
TL;DR: The structure of rabbit SERCA1a suggests a mechanism for selective Ca2+ loading and activation of SERCA, and provides new insight into how SLN and PLB inhibition arises from stabilization of this E1 intermediate state without bound Ca2+.
201
Intracellular Targeting Signals and Lipid Specificity Determinants of the ALA/ALIS P4-ATPase Complex Reside in the Catalytic ALA α-Subunit
Rosa L. López-Marqués,Lisbeth R. Poulsen,Susanne Hanisch,Katharina Meffert,Morten J. Buch-Pedersen,Mia K. Jakobsen,Thomas Günther Pomorski,Thomas Günther Pomorski,Michael G. Palmgren +8 more
TL;DR: It is demonstrated that cellular targeting and lipid specificity of P4-ATPases require the α- subunit but are independent of the β-subunit, which indicates that the flippase machinery is composed of two pieces.
98