Morrison B. Mac
Exelixis
49 Papers
705 Citations
Morrison B. Mac is an academic researcher from Exelixis. The author has contributed to research in topics: Kinase & Ovarian cancer. The author has an hindex of 14, co-authored 49 publications.
Chat about Author
Papers
Patent
Kinase Modulators and Methods of Use
Neel Kumar Anand,Charles M. Blazey,Owen Joseph Bowles,Joerg Bussenius,Lynne Canne Bannen,Diva Sze-Ming Chan,Baili Chen,Erick Wang Co,Simona Costanzo,Steven Charles Defina,Larisa Dubenko,Maurizio Franzini,Ping Huang,Vasu Jammalamadaka,Richard George Khoury,Moon Hwan Kim,Rhett Ronald Klein,Donna T. Le,Morrison B. Mac,John M. Nuss,Jason Jevious Parks,Kenneth D. Rice,Tsze H. Tsang,Amy Lew Tsuhako,Yong Wang,Wei Xu +25 more
- 22 Apr 2005
TL;DR: In this article, compounds of the Formula (I and II) wherein R, R21, R25-R33, m, n, X21-X23, and Q1 are defined are defined.
138
Patent
c-MET MODULATORS AND METHOD OF USE
Lynne Canne Bannen,Diva Sze-Ming Chan,Jeff Chen,Lisa Esther Dalrymple,Timothy Patrick Forsyth,Tai Phat Huynh,Vasu Jammalamadaka,Richard George Khoury,James W. Leahy,Morrison B. Mac,Grace Mann,Larry W. Mann,John M. Nuss,Jason Jevious Parks,Craig Stacy Takeuchi,Yong Wang,Wei Xu +16 more
- 24 May 2007
TL;DR: In this paper, the authors provide compounds for modifying protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion.
111
Patent
Phosphatidylinositol 3-kinase inhibitors and methods of their use
William Bajjalieh,Lynne Canne Bannen,S. David Brown,Patrick Kearney,Morrison B. Mac,Marlowe Charles K,John M. Nuss,Zerom Tesfai,Yong Wang,Wei Xu +9 more
- 09 Oct 2006
TL;DR: In this paper, small molecule inhibitors of PI3K are used for treating, preventing, and/or inhibiting malignancies such as ovarian cancer, cervical cancer, breast cancer, colon cancer, rectal cancer, and glioblastomas.
110
Patent
Pyrrole Derivatives As Pharmaceutical Agents
Lynne Canne Bannen,Jeff Chen,Lisa Esther Dalrymple,Brenton T. Flatt,Timothy Patrick Forsyth,Xiao-Hui Gu,Morrison B. Mac,Larry W. Mann,Grace Mann,Richard Martin,Raju Mohan,Brett Murphy,Michael Charles Nyman,William C. Stevens,Tie-Lin Wang,Yong Wang,Wu Jason H +16 more
- 30 Jul 2005
TL;DR: In this paper, compounds, compositions and methods for modulating the activity of receptors are provided for the treatment, prevention, or amelioration of one or more symptoms of disease or disorder directly or indirectly related to the activation of the receptors.
58
Patent
Inhibitors of the hedgehog pathway
Suleyman Bahceci,William Bajjalieh,Jeff Chen,Sergey Epshteyn,Timothy Patrick Forsyth,Tai Phat Huynh,Byung Gyu Kim,James W. Leahy,Matthew Sangyup Lee,Gary L. Lewis,Morrison B. Mac,Grace Mann,Marlowe Charles K,Brian Hugh Ridgway,Joan C. Sangalang,Xian Shi,Craig Stacy Takeuchi,Yong Wang,Zerom Tesfai +18 more
- 13 Mar 2008
TL;DR: In this paper, a compound of Formula (I) or a single isomer thereof is presented, where the compound is optionally as a pharmaceutically acceptable salt, hydrate, solvate or combination thereof.
52