Moritz Hardt
University of Erlangen-Nuremberg
4 Papers
Moritz Hardt is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Electrospinning & Mesenchymal stem cell. The author has an hindex of 4, co-authored 4 publications.
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Papers
Novel approach towards aligned PCL-Collagen nanofibrous constructs from a benign solvent system
Dirk Dippold,Aijia Cai,Moritz Hardt,Aldo R. Boccaccini,Raymund E. Horch,Justus P. Beier,Dirk W. Schubert +6 more
TL;DR: Aligned Polycaprolactone-Collagen (PCL-Coll) biocomposite nanofibers were fabricated via electrospinning using environmentally benign diluted acetic acid (AcOH) as solvent and ultrasonic treatment was introduced to enhance the intrinsically weak solubility of PCL in AcOH.
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Myogenic differentiation of primary myoblasts and mesenchymal stromal cells under serum-free conditions on PCL-collagen I-nanoscaffolds
Aijia Cai,Moritz Hardt,Paul Schneider,Rafael Schmid,Claudia Lange,Dirk Dippold,Dirk W. Schubert,Anja M. Boos,Annika Weigand,Andreas Arkudas,Raymund E. Horch,Justus P. Beier,Justus P. Beier +12 more
TL;DR: This study was able to myogenically differentiate mesenchymal stromal cells with myoblasts on PCL-collagen I-nanoscaffolds in a serum-free medium, applicable to future clinical applications since no xenogenous substances were used.
Mesenchymal stem cells and myoblast differentiation under HGF and IGF-1 stimulation for 3D skeletal muscle tissue engineering
R. Witt,Annika Weigand,Anja M. Boos,Aijia Cai,Dirk Dippold,Aldo R. Boccaccini,Dirk W. Schubert,Moritz Hardt,Claudia Lange,Andreas Arkudas,Raymund E. Horch,Justus P. Beier +11 more
TL;DR: MSCs could be successfully differentiated into the myogenic lineage both in mono- and in co-cultures independent of HGF and IGF-1 stimulation by expressing desmin, myocyte enhancer factor 2, myosin heavy chain 2 and alpha-sarcomeric actinin.
Investigation of the batch-to-batch inconsistencies of Collagen in PCL-Collagen nanofibers.
Dirk Dippold,Aijia Cai,Moritz Hardt,Aldo R. Boccaccini,Raymund E. Horch,Justus P. Beier,Dirk W. Schubert +6 more
TL;DR: The application of tissue engineered constructs is an approach in regenerative therapies to support regeneration of damaged muscular tissue and the development of highly aligned electrospun scaffolds based on polycaprolactone (PCL) and collagen enables a versatile development towards tailor made applications.