Morgane Pertuit
Laboratory of Molecular Biology
16 Papers
107 Citations
Morgane Pertuit is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: MAPK/ERK pathway & cAMP-dependent pathway. The author has an hindex of 10, co-authored 15 publications. Previous affiliations of Morgane Pertuit include Hoffmann-La Roche & Aix-Marseille University.
Chat about Author
Papers
Genetic analysis in young patients with sporadic pituitary macroadenomas: besides AIP don't forget MEN1 genetic analysis
Thomas Cuny,Morgane Pertuit,M Sahnoun-Fathallah,Adrian Daly,Gianluca Occhi,Marie Françoise Odou,Antoine Tabarin,Marie Laure Nunes,Brigitte Delemer,Vincent Rohmer,Rachel Desailloud,Véronique Kerlan,Olivier Chabre,Jean-Louis Sadoul,M. Cogne,Philippe Caron,Christine Cortet-Rudelli,Anne Lienhardt,Isabelle Raingeard,Anne-Marie Guedj,Thierry Brue,Albert Beckers,Georges Weryha,Alain Enjalbert,Anne Barlier +24 more
TL;DR: Mutations in MEN1 can be of significance in young patients with sporadic isolated pituitary macroadenomas, particularly PRL, and together with AIP, are suggested to suggest genetic analysis of MEN1 in such a population.
Regulation of the RAP1/RAF-1/Extracellularly Regulated Kinase-1/2 Cascade and Prolactin Release by the Phosphoinositide 3-Kinase/AKT Pathway in Pituitary Cells
David Romano,Morgane Pertuit,Ramahefarizo Rasolonjanahary,Jean-Vianney Barnier,Karine Magalon,Alain Enjalbert,Corinne Gerard +6 more
TL;DR: Findings indicate that the PI3K/Akt pathway exerts dual regulatory effects on both the Rap1/Raf-1/ERK- 1/2 cascade and PRL release in pituitary cells, i.e. negative effects in unstimulated cells and positive ones in IGF-I-stimulated cells.
38
Signalling Pathway Alterations in Pituitary Adenomas: Involvement of Gsα, cAMP and Mitogen-Activated Protein Kinases
TL;DR: A crucial role for ERK1/2 in GH‐secreting adenomas downstream of cAMP pathway alterations that might impact the tumoural phenotype is postulated.
34
Case Report of GNAS Epigenetic Defect Revealed by a Congenital Hypothyroidism
Pauline Romanet,Lindsay Osei,Irene Netchine,Morgane Pertuit,Alain Enjalbert,Rachel Reynaud,Anne Barlier,Anne Barlier +7 more
TL;DR: A case of PHP caused by epigenetic changes in GNAS in a patient with congenital hypothyroidism is reported, adding a new cause of the disease to the known onsets of PHP1B and emphasizes the need for a new PHP classification system.
30
18F‐FDG PET/CT as a predictor of hereditary head and neck paragangliomas
Elise M. Blanchet,Sophie Gabriel,Victoria Martucci,Nicolas Fakhry,Clara C. Chen,Arnaud Deveze,Corina Millo,Anne Barlier,Morgane Pertuit,Anderson Loundou,Karel Pacak,David Taïeb +11 more
TL;DR: The aim of this study was to evaluate the relationship between 18F‐FDG uptake and the SDHx mutation status in HNPGL patients.
29