Monika Schmidt
University of Erlangen-Nuremberg
14 Papers
57 Citations
Monika Schmidt is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: T cell & Biology. The author has an hindex of 9, co-authored 11 publications.
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Papers
Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23
Rubén Martínez-Barricarte,Janet Markle,Cindy S. Ma,Elissa K. Deenick,Noé Ramírez-Alejo,Federico Mele,Daniela Latorre,Seyed Alireza Mahdaviani,Caner Aytekin,Davood Mansouri,Vanessa L. Bryant,Vanessa L. Bryant,Vanessa L. Bryant,Fabienne Jabot-Hanin,Caroline Deswarte,Caroline Deswarte,Alejandro Nieto-Patlán,Laura Surace,Gaspard Kerner,Gaspard Kerner,Yuval Itan,Yuval Itan,Sandra Jovic,Danielle T. Avery,Natalie Wong,Geetha Rao,Etienne Patin,Etienne Patin,Satoshi Okada,Benedetta Bigio,Bertrand Boisson,Bertrand Boisson,Bertrand Boisson,Franck Rapaport,Yoann Seeleuthner,Yoann Seeleuthner,Monika Schmidt,Aydan Ikinciogullari,Figen Dogu,Gönül Tanır,Payam Tabarsi,Mohammed Reza Bloursaz,Julia K. Joseph,Avneet Heer,Xiao-Fei Kong,Mélanie Migaud,Mélanie Migaud,Tomi Lazarov,Frederic Geissmann,Frederic Geissmann,Frederic Geissmann,Bernhard Fleckenstein,Cecilia S. Lindestam Arlehamn,Alessandro Sette,Alessandro Sette,Anne Puel,Anne Puel,Anne Puel,Jean-François Emile,Esther van de Vosse,Lluis Quintana-Murci,Lluis Quintana-Murci,James P. Di Santo,Laurent Abel,Laurent Abel,Laurent Abel,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Jacinta Bustamante,Stuart G. Tangye,Federica Sallusto,Jean-Laurent Casanova +72 more
TL;DR: These experiments of nature show that human IL-12 and IL-23 are both required for optimal IFN-γ–dependent immunity to mycobacteria, both individually and much more so cooperatively.
Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections
Amandine Crequer,Anja Troeger,Etienne Patin,Cindy S. Ma,Capucine Picard,Vincent Pedergnana,Claire Fieschi,Annick Lim,Avinash Abhyankar,Laure Gineau,Ingrid Mueller-Fleckenstein,Monika Schmidt,Alain Taïeb,James G. Krueger,Laurent Abel,Stuart G. Tangye,Gérard Orth,David A. Williams,Jean-Laurent Casanova,Emmanuelle Jouanguy +19 more
TL;DR: It is concluded that RHOH deficiency leads to T cell defects and persistent EV- HPV infections, suggesting that T cells play a role in the pathogenesis of chronic EV-HPV infections.
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Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood
Minji Byun,Cindy S. Ma,Cindy S. Ma,Arzu Akcay,Vincent Pedergnana,Vincent Pedergnana,Umaimainthan Palendira,Umaimainthan Palendira,Jinjong Myoung,Danielle T. Avery,Yifang Liu,Avinash Abhyankar,Lazaro Lorenzo,Lazaro Lorenzo,Monika Schmidt,Hye Kyung Lim,Olivier Cassar,Mélanie Migaud,Mélanie Migaud,Flore Rozenberg,Nur Canpolat,Gonul Aydogan,Bernhard Fleckenstein,Jacinta Bustamante,Jacinta Bustamante,Capucine Picard,Capucine Picard,Antoine Gessain,Emmanuelle Jouanguy,Emmanuelle Jouanguy,Emmanuelle Jouanguy,Ethel Cesarman,Martin Olivier,Philippe Gros,Laurent Abel,Laurent Abel,Laurent Abel,Michael Croft,Stuart G. Tangye,Stuart G. Tangye,Jean-Laurent Casanova +40 more
TL;DR: Human OX40 is necessary for robust CD4+ T cell memory and confers selective protective immunity against HHV-8 infection in endothelial cells.
Activation of Noncanonical NF-κB Signaling by the Oncoprotein Tio *
Sarah Jill de Jong,Jens-Christian Albrecht,Monika Schmidt,Ingrid Müller-Fleckenstein,Brigitte Biesinger +4 more
TL;DR: The Tio oncoprotein triggers noncanonical NF-κB signaling through NEMO-dependent up-regulation of p100 precursor and RelB, as well as through NemO-independent generation of p52 effector, which disrupts the continuous growth of the transformed cells and induces cell death.
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T-Cell Growth Transformation by Herpesvirus Saimiri Is Independent of STAT3 Activation
Elke Heck,Doris Lengenfelder,Monika Schmidt,Ingrid Müller-Fleckenstein,Bernhard Fleckenstein,Brigitte Biesinger,Armin Ensser +6 more
TL;DR: Introducing a tyrosine-to-phenylalanine mutation in the YXPQ motif of Tip of HVS C488 demonstrates that growth transformation by HVS is independent of STAT3 activation.
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