Moises Hernández
University of Murcia
5 Papers
31 Citations
Moises Hernández is an academic researcher from University of Murcia. The author has contributed to research in topics: Endothelial dysfunction & Medicine. The author has an hindex of 4, co-authored 5 publications.
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Papers
2-methoxyestradiol plasma levels are associated with clinical severity indices and biomarkers of preeclampsia.
Miriam Pertegal,Francisco J. Fenoy,Bárbara Bonacasa,Jaime Mendiola,Juan L. Delgado,Moises Hernández,Miguel G. Salom,Vicente Bosch,Isabel Hernández +8 more
TL;DR: Patients with PE had lower 2ME levels that were correlated with different clinical indices and biomarkers of severity, indicating that 2ME could be taken into account for the clinical management of this syndrome.
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Acute effects of 2-methoxyestradiol on endothelial aortic No release in male and ovariectomized female rats.
Francisco J. Fenoy,María E. Hernandez,Moises Hernández,Tomás Quesada,Miguel G. Salom,Isabel Hernández +5 more
TL;DR: 2-Methoxyestradiol appears to be a promising pharmacological agent capable of improving endothelial function in men and postmenopausal women.
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Fetal Val108/158Met catechol-O-methyltransferase (COMT) polymorphism and placental COMT activity are associated with the development of preeclampsia
Miriam Pertegal,Francisco J. Fenoy,Moises Hernández,Jaime Mendiola,Juan L. Delgado,Bárbara Bonacasa,Andrés Corno,Bernardo López,Vicente Bosch,Isabel Hernández +9 more
TL;DR: Fetal Met-Met COMT genotype reduces COMT placental expression and activity in vitro and increases preeclampsia, risk but it does not explain the difference in maternal 2-ME levels between preeclamptic and normal pregnancies.
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Endothelial dysfunction in gestational hypertension induced by catechol‐O‐methyltransferase inhibition
Moises Hernández,Isabel Hernández,Francisca Rodriguez,M Pertegal,Bárbara Bonacasa,Miguel G. Salom,Tomás Quesada,Francisco J. Fenoy +7 more
TL;DR: Evidence is provided that inhibition of catechol‐O‐methyltransferase in pregnant rats produces arterial hypertension and endothelial dysfunction due to reduced nitric oxide bioavailability and support a possible new approach to early diagnosis and treatment of the disease.
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Biomarkers of Preeclampsia 2-Methoxyestradiol Plasma Levels Are Associated With Clinical Severity Indices and
Raghvendra K. Dubey,Edwin K. Jackson,Moises Hernández,Miguel G. Salom,Vicente Bosch,Francisco J. Fenoy,Bárbara Bonacasa,Jaime Mendiola,Juan L. Delgado,Tim Lahm,Rubin M. Tuder,Irina Petrache +11 more
- 01 Jan 2015
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