Mohan Pauliah
Kettering University
12 Papers
71 Citations
Mohan Pauliah is an academic researcher from Kettering University. The author has contributed to research in topics: Iron oxide nanoparticles & Sentinel lymph node. The author has an hindex of 7, co-authored 12 publications. Previous affiliations of Mohan Pauliah include Memorial Sloan Kettering Cancer Center.
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Papers
Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth
Sung Eun Kim,Li Zhang,Kai Ma,Michelle Riegman,Feng Chen,Irina Ingold,Marcus Conrad,Melik Z. Turker,Minghui Gao,Xuejun Jiang,Xuejun Jiang,Sebastien Monette,Mohan Pauliah,Mithat Gonen,Pat Zanzonico,Thomas P. Quinn,Ulrich Wiesner,Michelle S. Bradbury,Michael Overholtzer,Michael Overholtzer +19 more
TL;DR: It is shown that ultrasmall (< 10 nm in diameter) poly(ethylene glycol) (PEG)-coated silica nanoparticles, functionalized with melanoma-targeting peptides, can induce a form of programmed cell death known as ferroptosis in starved cancer cells and cancer-bearing mice.
Cancer-Targeting Ultrasmall Silica Nanoparticles for Clinical Translation: Physicochemical Structure and Biological Property Correlations
Feng Chen,Kai Ma,Miriam Benezra,Li Zhang,Sarah M. Cheal,Evan H. Phillips,Barney Yoo,Mohan Pauliah,Michael Overholtzer,Pat Zanzonico,Sonia Sequeira,Mithat Gonen,Thomas P. Quinn,Ulrich Wiesner,Michelle S. Bradbury +14 more
TL;DR: The synthesis, characterization, and long-term stability of ultrasmall (<10 nm diameter) dual-modality and integrintargeting silica nanoparticles and the extent to which their surface ligand density differentially modulates key in vitro and in vivo biological activities in melanoma models are reported on.
Patent
Systems, methods, and apparatus for multichannel imaging of fluorescent sources in real-time
Michelle S. Bradbury,Ulrich Wiesner,Richard J. C. Meester,Snehal G. Patel,Nadeem R. Abu-Rustum,Mohan Pauliah +5 more
- 31 Dec 2014
TL;DR: In this paper, a multichannel imaging system capable of detecting and distinguishing multiple fluorescent light sources simultaneously is presented, and methods of using the system to image disease or cellular abnormalities for diagnostic and/or intraoperative purposes.
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Intraoperative mapping of sentinel lymph node metastases using a clinically translated ultrasmall silica nanoparticle.
TL;DR: A first-in-kind ultrasmall tumor-targeting inorganic (silica) nanoparticle is designed to overcome translational challenges and serve as an intraoperative treatment tool for guiding resection of cancerous lymph nodes.
Tumor-associated macrophages, nanomedicine and imaging: the axis of success in the future of cancer immunotherapy.
TL;DR: The key cogitations that influence TME, TAM modulations and immunotherapy in solid tumors as well as the methods and resources of tracking the tumor response are discussed.
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