Mohammed El Mabrouk
Université de Montréal
17 Papers
188 Citations
Mohammed El Mabrouk is an academic researcher from Université de Montréal. The author has contributed to research in topics: Angiotensin II & Vascular smooth muscle. The author has an hindex of 13, co-authored 17 publications.
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Papers
p38 MAP Kinase Regulates Vascular Smooth Muscle Cell Collagen Synthesis by Angiotensin II in SHR But Not in WKY
TL;DR: Differential roles of ERK1/2 and p38 MAP kinase in AT1-stimulated VSMC growth and collagen production are indicated, which may contribute to vascular remodeling in hypertension.
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Differential activation of extracellular signal-regulated protein kinase 1/2 and p38 mitogen activated-protein kinase by AT1 receptors in vascular smooth muscle cells from Wistar-Kyoto rats and spontaneously hypertensive rats
Rhian M. Touyz,Gang He,Mohammed El Mabrouk,Quy N. Diep,Vartan Mardigyan,Ernesto L. Schiffrin +5 more
TL;DR: The results suggest that angiotensin II activates numerous MAP kinases in VSMCs and that differential activation of these kinases may be important in altered growth signaling inVSMCs from SHR.
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Effect of AT1 receptor blockade on cardiac apoptosis in angiotensin II-induced hypertension
TL;DR: Angiotensin II (ANG II) via AT1 receptors induces apoptosis in cardiomyocytes in vitro and the hypothesis that in vivo AT1 receptor stimulation is accompanied by cardiac apoptosis and attemp...
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Differential ANG II-induced growth activation pathways in mesenteric artery smooth muscle cells from SHR.
TL;DR: Investigation of angiotensin II-induced growth signaling mechanisms in vascular smooth muscle cells from mesenteric arteries of spontaneously hypertensive (SHR) and Wistar-Kyoto rats found it stimulates VSMC proliferation via AT(1) and AT(2) receptors in SHR and in WKY, which could contribute to vascular remodeling inSHR.
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Signaling pathways implicated in oncostatin M-induced aggrecanase-1 and matrix metalloproteinase-13 expression in human articular chondrocytes.
TL;DR: Results suggest that OSM-stimulated ADAMTS-4 and MMP-13 expression is mediated by ERK1/2, JAK3/STAT1/3 and PI3K/Akt and by cross talk between these pathways.
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