Mitsuo Oshimura
Tokyo Medical and Dental University
11 Papers
220 Citations
Mitsuo Oshimura is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Chromosomal translocation & Chronic myelogenous leukemia. The author has an hindex of 8, co-authored 11 publications. Previous affiliations of Mitsuo Oshimura include Showa University.
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Papers
A summary of cytogenetic studies on 534 cases of chronic myelocytic leukemia in Japan
Takaaki Ishihara,Motomichi Sasaki,Mitsuo Oshimura,Nanao Kamada,Kiyomi Yamada,Michiko Okada,Masaharu Sakurai,Taketoshi Sugiyama,Yukimasa Shiraishi,Sei-ichi Kohno +9 more
TL;DR: The results of the analysis of the data were in substantial accord with those of the First International Workshop on Chromosomes in Leukemia and other published data, but certain differences were noted in the frequency of Philadelphia chromosome (Ph1)-negative cases, unusual and complex Ph1 translocations, and additional chromosome changes.
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Variant Ph1 translocations in CML and their incidence, including two cases with sequential lymphoid and myeloid crises
Mitsuo Oshimura,Mitsuo Oshimura,Kazuma Ohyashiki,Kazuma Ohyashiki,Hideo Terada,Hideo Terada,Fumimaro Takaku,Fumimaro Takaku,Akira Tonomura,Akira Tonomura +9 more
TL;DR: The evidence supports the notion of "lymphoid-myeloid" multipotentiality of certain leukemic cells in chronic myelogenous leukemia cases and appears that the incidence of such a "masked" Ph1 is less than 0.6% in CML cases.
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Cytogenetic and ultrastructural studies on ten patients with acute promyelocytic leukemia, including one case with a complex translocation
Kazuma Ohyashiki,Mitsuo Oshimura,Hiroyuki Uchida,Saiko Nomoto,Nobuhiko Sakai,Akira Tonomura,Hisao Ito +6 more
TL;DR: Chromosomal banding analyses and ultrastructural studies were performed on ten cases of acute promyelocytic leukemia (APL-M3) in this article, where a reciprocal translocation, t(15q + ;17q-), was found in six of them, and the possible breakpoints of these chromosomes were assigned at bands 15q22 and 17q12.
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A summary of cytogenetic, morphologic, and clinical data on t(8q−;21q+) and t(15q+;17q−) translocation leukemias in Japan
Masaharu Sakurai,Motomichi Sasaki,Nanao Kamada,Michiko Okada,Mitsuo Oshimura,Takaaki Ishihara,Yukimasa Shiraishi +6 more
TL;DR: The t(8q - ;21q+) translocation seems to be more common as an abnormality in ANLL in Japan as compared to findings in other countries; the high incidence of t(15q + ;17q-) among Japanese patients with APL indicated in this study still awaits confirmation.
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Chronic myelogenous leukemia with a complex Ph1 translocation in an XYY male.
Kazuma Ohyashiki,Mitsuo Oshimura,Takayo Toyoda,Nobuhiko Sakai,Hisao Ito,Kohtaro Yamamoto,Akira Tonomura +6 more
TL;DR: The presence of the complex Ph1 translocation in the B-lymphocyte cell line suggests that some of the B lymphocytes in this patient originated from the CML clone.
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