In the search for novel antibacterial, the fruit peel of a medicinal plant: Persea americana Mill was investigated for activity. The study was to evaluate the antibacterial efficacy of the crude ethanolic and aqueous extract of the fruit peel of Persea americana Mill against selected clinical isolates. The agar well diffusion method was used in the study. Phytochemical screening was conducted on plants which revealed the presence of saponin, fixed oils, carbohydrates, tannins, reducing sugars, protein, steroids, terpenoids and phlobatannins in both extract in addition to the aforementioned phytochemicals, anthranal glycoside was present only in the aqueous extract while alkaloids was present in the ethanolic extract. The treatments with significant activity were between 125 to 500 mg/ml for the antibacterial. Antibacterial disc was incorporated to check for the sensitivity of the bacteria, E. coli, P. vulgaris and S. typhi showed 50, 0 and 10% resistance respectively. The result of the antibacterial screening revealed the sensitivity of the bacteria to ethanol extract in this order E. coli> S. typhi> P. vulgaris with mean zones of inhibition ranging from 6 to 14, 3 to 15 and 3 to 8 mm respectively. For aqueous extract; S. typhi> S. vulgaris>E. coli with mean zone of inhibition ranging from 0 to 15, 0 to 4 and 0 mm respectively. There was a significant difference between the activity of the aqueous extract and ethanolic extract against these bacteria at 95% confidence level. The general results of the evaluation considered the plant as a very potential source of novel antibacterial agents against Enterobacteriacea and ethanol, a better extracting solvent.

Antibacterial screening of the ethanol and aqueous extract of the fruit peel of Persea americana Mill. against selected enteric bacteria

Tanaman alpukat (Persea americana Mill) merupakan tanaman yang dapat tumbuh subur didaerah tropis seperti Indonesia dan merupakan salah satu jenis buah yang digemari oleh masyarakat karena rasanya yang enak. Penggunaan daging buah alpukat pada penelitian ini dikarenakan daging buah alpukat memiliki kandungan senyawa antibakteri seperti saponin, tanin, alkaloid, flavanoid, steroid, dan fenol. Tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri daging buah alpukat dan ekstrak etanol daging buah alpukat terhadap Escherichia coli pada konsentrasi 30%, 50%, dan 70% menggunakan metode difusi agar, siprofloksasin sebagai kontrol positif dan DMSO sebagai kontrol negatif. Metode ekstraksi dilakukan dengan metode maserasi menggunakan pelarut etanol 96%, buah alpukat yang berwarna hijau. Hasil uji daya hambat dengan konsentrasi ekstrak etanol daging buah alpukat 30%, 50%, dan 70% dapat menghambat pertumbuhan Escherichia coli dengan rata-rata diameter zona hambat 11,45 mm, 12,42 mm, dan 13,95 mm, dan kontrol positif siprofloksasin adalah 25,94 mm. Zona hambat rata-rata pada  daging buah alpukat 8,9 mm, 7,73 mm, dan 6,66 mm pada konsentrasi 30%, 50%, dan 70% dan kontrol positif siprofloksasin adalah 28,56 mm. Dari hasil diatas dapat diambil kesimpulan bahwa daging buah alpukat dan ekstrak etanol daging buah alpukat (Persea americana Mill) memiliki aktivitas antibakteri terhadap Escherichia coli.

Uji Aktivitas Antibakteri Daging Buah Alpukat Dan Ekstrak Etanol Daging Buah Alpukat (Persea Americana Mill) Terhadap Escherichia coli

Avocado (Parsea americana Mill) is a fruit that can grow in tropical and subtropical areas. Avocado (Parsea americana Mill) has a delicious taste so it is favored by many Indonesian people. This study aims to determine the levels of flavonoids in the skin of long green avocados, round green avocados and round red avocados. Avocado peel powder is extracted by maceration. The solvent used is ethanol solvent. The standard solution used was quercetin standard solution with various concentrations of 5%, 20%, 40%, 60%, 80% and 100%. Determination of total flavonoid levels using UV-Vis spectrophotometry with a wavelength of 431 nm. The results showed that the levels of flavonoids in the long green avocado skin were 1614,286 mg/100g, round green avocado 1340,476 mg/100g and round red avocado 1385,714 mg/100g.

Analisis Kadar Flavonoid Kulit Buah Alpukat ( Persea americana Mill) Yang Beredar di Pasar Inpres Palu Analysis of Flavonoid Levels in Avocado Skin (Parsea americana Mill) Circulating in the Inpres Palu Market

Jerawat merupakan salah satu penyakit kulit yang pada umumnya muncul pada pria dan wanita pada masa pubertas yang biasa disebabkan bakteri P. acnes. Penggunaan antibiotik sebagai anti jerawat dapat menyebabkan iritasi. Buah alpukat (P. americana Mill.) merupakan salah satu tanaman yang banyak dijumpai di Indonesia, namun pemanfaatannya sebagai tanaman obat masih sedikit diteliti. Buah alpukat diketahui mempunyai senyawa antibakteri seperti alkaloid, flavaoid, saponin dan tanin. Tujuan dari penelitian ini untuk mengetahui stabilitas fisik dari sediaan salep dan daya hambatnya dalam pertumbuhan P. acnes. Penelitian ini merupakan penelitian eksperimental, simplisia buah alpukat sebanyak 250 g diektraksi dengan metode maserasi menggunakan etanol 96%. Ekstrak yang dihasilkan dibuat menjadi 3 formula salep dengan konsentrasi 10%, 15% dan 20%. Pengujian zona hambat bakteri P. acnes menggunakan metode sumuran. Hasil uji dianalisis menggunakan One Way ANOVA dan Kruskal-Wallis. Hasil penelitian menunjukkan bahwa FI, FII dan FIII mampu memenuhi sifat fisik salep yang baik namun sifat fisik daya sebar tidak memenuhi kriteria. Daya hambat pertumbuhan bakteri untuk FI, FII dan FIII masing-masing dengan diameter zona hambat sebesar 15,96±0,351 mm, 14,4±0,721 mm dan 13,06±0,503 mm. Kesimpulan dari penelitian ini yaitu semua formula dapat dijadikan salep dan dapat menghambat pertumbuhan bakteri Propionibacterium acnes. Diharapkan peneliti selanjutnya dapat mengembangkan formulasi dalam bentuk sediaan lain dan menggunakan bakteri penyebab jerawat lainnya untuk mengetahui kemampuan ekstrak etanol buah alpukat dalam menghambat pertumbuhan bakteri. 

pdf/formulasi-dan-uji-aktivitas-antijerawat-sediaan-salep-dari-2r89huu9iq.pdf

Formulasi dan Uji AKtivitas Antijerawat Sediaan Salep Dari Ekstrak Etanol Buah Alpukat (Persea americana Mill.) Terhadap Bakteri Propionibacterium acnes

Avocados are known as antibacterial because of the content of antibacterial compounds such as saponins, alkaloids, and flavonoids in the fruit and leaves. Avocado extract skin has a higher content of carotene, total phenolic and flavonoids than the fruit meat. Total phenolic content and antioxidant potential of avocado phenol are influenced by solvent extract and avocado type. The skin and seeds have a higher phenolic content than the fruit flesh. Avocado skin and seeds also have greater antioxidant ability in test tubes. Phenolic compounds found showed antioxidant activity in vitro. This study aims to determine whether avocado bark extract has antimicrobial activity against Staphylococcus aureus bacteria. This research is an experimental study using disc diffusion. The results of this study found testing of lemongrass leaf extract (Cymbopogonnardus) with a concentration of 25%, 50%, 75%, 100%, influencing the growth of Staphylococcus aureus bacteria. This study shows that avocado peels affect the growth of Staphylococcus aureus bacteria .

/pdf/uji-efektivitas-antibakteri-dengan-kulit-buah-alpukat-persea-42mzhl582e.pdf

UJI EFEKTIVITAS ANTIBAKTERI DENGAN KULIT BUAH ALPUKAT(Persea americana Mill) SEBAGAI OBJEK UNTUK DIAMBIL EKSTRAKNYA DENGAN BIOINDIKATOR BAKTERI Staphylococcus aureus

Handle everyday research tasks with reliable, citation-backed results

Your personal Research Agent to handle research tasks with citation-backed results

Popular Tasks used by Researchers

How can I help with your research?

Meet SciSpace

Get more enhanced response by uploading the PDFs you want me to reference.

No relevant PDFs in your library

SciSpace is the AI research assistant for academics. Run systematic literature reviews on 280M+ papers, and write papers with cited sources. Trusted by 1M+ students, PhDs & researchers.

SciSpace | AI for Research

Analyze PDFs

Code & Manuscripts

Funding & Grants

Literature & Patents

Medical & Clinical Data

Systematic Review

Visualize & Present

Web & Data

Build a Google Scholar-like website for your research.

Build a website

Create charts and images for your research

Create a Chart

Write a paper for submission to a journal

Draft a manuscript

Patent Search

Design eye-catching scientific posters in minutes.

Scientific Poster Generation

Systematic Literature Review

One task is running at the moment. Your messages will be shown right after.

Drag and drop or click here to browse

Loved by <highlight>1 million+</highlight> researchers

Extract a list of specific topics and their sources from unstructured text

Topics

Compare and analyze relevant papers that matches with your search

Papers

Get insights from PDFs and bookmarked papers from your library

My library

Recent searches

Try searching for:

Catch AI-generated content in scholarly and non-scholarly content

{ai} Detector

Ai Writer

Get PDF Summaries, highlighted text explanations 

Chat with PDF

Effortlessly create in-text citations and bibliographies in APA and 2,500 other formats

Citation generator

Get explanations, summaries, and answers on academic papers

Ease up your research workflow with {scispace}'s cohort of exciting AI tools

Elevate your academic writing skills and convey your ideas the way you want

Paraphraser

Explore our range of reading and writing tools

Your file is being prepared and should be ready in a few minutes. If it's a large file, it might take a bit longer. You can close this window, and we'll email you the file when it's done.

You have reached a maximum limit of <strong>{limit}</strong> columns in the table. Remove at least <strong>1</strong> column to add or create another one.

Mirna Jayustin

Author Tools

Chat about Author

Papers

UJI EFEKTIVITAS ANTIBAKTERI DENGAN KULIT BUAH ALPUKAT(Persea americana Mill) SEBAGAI OBJEK UNTUK DIAMBIL EKSTRAKNYA DENGAN BIOINDIKATOR BAKTERI Staphylococcus aureus