Mirjam Widmer
23 Papers
38 Citations
Mirjam Widmer is an academic researcher. The author has contributed to research in topics: Mass spectrometry & Chemistry. The author has an hindex of 13, co-authored 20 publications.
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Papers
Comprehensive comparison of liquid chromatography selectivity as provided by two types of liquid chromatography detectors (high resolution mass spectrometry and tandem mass spectrometry): “Where is the crossover point?”
TL;DR: The data indicated that the selectivity of LC-HRMS exceeds LC-MS/MS, if high resolution mass spectrometry (HRMS) data is recorded with a resolution of 50,000 full width at half maximum (FWHM) and a corresponding mass window.
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Development of an improved high resolution mass spectrometry based multi-residue method for veterinary drugs in various food matrices.
TL;DR: Significantly better performance parameters were obtained when comparing the new method with the older, TOF based method, attributed to the higher resolution (50,000 versus 12,000 FWHM) and the superior mass stability of the of the Orbitrap over the previously utilized TOF instrument.
145
Ultra-performance liquid chromatography coupled to time of flight mass spectrometry (UPLC-TOF): a novel tool for multiresidue screening of veterinary drugs in urine.
TL;DR: The usefulness of metabolites as additional confirmation criteria for positive findings is discussed and a revisiting of the identification point system is suggested in the light of additional resolution, as provided by the TOF and the UPLC technology.
137
Quantitative LC/MS-MS determination of sulfonamides and some other antibiotics in honey.
TL;DR: A simple and rapid method was developed for the determination of 20 antibiotics in honey by liquid chromatography tandem mass spectrometry and a hydrolysis step ensures the liberation of sugar-bound sulfonamides.
95
Determination of nitrofuran and chloramphenicol residues by high resolution mass spectrometry versus tandem quadrupole mass spectrometry
TL;DR: An ultra-high performance liquid chromatography based method, coupled to high resolution mass spectrometry (UHPLC-HRMS), was developed to permit the detection and quantification of various nitrofuran and chloramphenicol residues in a number of animal based food products.
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