Minghui Cao
Sun Yat-sen University
25 Papers
56 Citations
Minghui Cao is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Medicine & Stem cell. The author has an hindex of 9, co-authored 15 publications. Previous affiliations of Minghui Cao include Memorial Hospital of South Bend.
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Papers
Targeted Magnetic Resonance Imaging and Modulation of Hypoxia with Multifunctional Hyaluronic Acid-MnO2 Nanoparticles in Glioma.
Chaoping Fu,Chaoping Fu,Xiaohui Duan,Minghui Cao,Shuqi Jiang,Xiaohua Ban,Na Guo,Fang Zhang,Jiaji Mao,Ting Huyan,Jun Shen,Li Ming Zhang +11 more
TL;DR: The results show that HA‐MnO2 NPs can be used for sensitive, targeted MRI detection of gliomas and simultaneous attenuation of tumor hypoxia and the downregulation of VEGF and HIF‐1α expression in intracranial glioma validates the sustained attenuation effect of HA‐ MnO 2 NPs on tumor Hypoxia.
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Theranostic Nanomedicine for Synergistic Chemodynamic Therapy and Chemotherapy of Orthotopic Glioma.
Junyi Tan,Xiaohui Duan,Fang Zhang,Xiaohua Ban,Jiaji Mao,Minghui Cao,Shisong Han,Xintao Shuai,Jun Shen +8 more
TL;DR: A theranostic nanodrug is developed by incorporating oleic acid‐modified manganese oxide (MnO) and temozolomide (TMZ) into a polyethylene glycol‐poly(2‐(diisopropylamino)ethyl methacrylate‐based polymeric micelle containing internalizing arginine‐glycine‐aspartic acid (iRGD).
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In vivo tracking of the tropism of mesenchymal stem cells to malignant gliomas using reporter gene-based MR imaging
Minghui Cao,Jiaji Mao,Xiaohui Duan,Liejing Lu,Fang Zhang,Bingling Lin,Meiwei Chen,Chushan Zheng,Xiang Zhang,Jun Shen +9 more
TL;DR: FTH reporter gene‐based MRI can be used to reliably track the tropism and fate of MSCs after their systemic transplantation in orthotopic glioma, and this real‐time in vivo tracking system will facilitate the future development of stem cell‐based therapies for malignant gliomas.
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The long-term fate of mesenchymal stem cells labeled with magnetic resonance imaging-visible polymersomes in cerebral ischemia.
Xiaohui Duan,Liejing Lu,Yong Wang,Fang Zhang,Jiaji Mao,Minghui Cao,Bingling Lin,Xiang Zhang,Xintao Shuai,Jun Shen +9 more
TL;DR: The results showed that MSCs could improve the functional outcome and reduce the infarct volume of stroke in the brain and in vivo MRI can verify the biodistribution and migration of grafted cells when pre-labeled with SPION-loaded polymersome.
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MRI-Visible siRNA Nanomedicine Directing Neuronal Differentiation of Neural Stem Cells in Stroke
Liejing Lu,Yong Wang,Fang Zhang,Meiwei Chen,Bingling Lin,Xiaohui Duan,Minghui Cao,Chushan Zheng,Jiaji Mao,Xintao Shuai,Jun Shen +10 more
TL;DR: A nanoscale polymersome is developed to codeliver superparamagnetic iron oxide nanoparticles and siRNA targeting NgR gene (siNgR) into NSCs and an improved recovery of neural function is achieved in rat ischemic stroke model.
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