Ming-Yan Wang
Fudan University
22 Papers
194 Citations
Ming-Yan Wang is an academic researcher from Fudan University. The author has contributed to research in topics: Trophoblast & Chemokine. The author has an hindex of 11, co-authored 22 publications. Previous affiliations of Ming-Yan Wang include Fudan University Shanghai Medical College.
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Papers
Blockade of CD86 Signaling Facilitates a Th2 Bias at the Maternal-Fetal Interface and Expands Peripheral CD4+CD25+ Regulatory T Cells to Rescue Abortion-Prone Fetuses
TL;DR: It was demonstrated that in vivo blockade of CD86 costimulation could suppress maternal immune attack to the fetus by shifting cytokines from Th1 predominance to Th2 bias at the maternal- Fetal interface, and expanding peripheral CD4+CD25+ regulatory T cells, which play an important role in the development and maintenance of maternal-fetal tolerance.
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The crosstalk between endometrial stromal cells and macrophages impairs cytotoxicity of NK cells in endometriosis by secreting IL-10 and TGF-β
Hui-Li Yang,Wen-Jie Zhou,Kai-Kai Chang,Jie Mei,Li-Qing Huang,Ming-Yan Wang,Yi Meng,Si-Yao Ha,Da-Jin Li,Ming-Qing Li +9 more
TL;DR: The interaction between macrophages and ESCs downregulates cytotoxicity of NK cells possibly by stimulating the secretion of IL-10 and TGF-β, and may further trigger the immune escape of ectopic fragments and promote the occurrence and the development of EMS.
Blockade of CD80 and CD86 at the time of implantation inhibits maternal rejection to the allogeneic fetus in abortion-prone matings.
TL;DR: It is indicated that blocking CD80 and CD86 enhanced maternal tolerance to her fetus in mice by increasing regulatory T cell function and skewing toward a Th2 response.
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Alterations of Several Serum Parameters Are Associated with Preeclampsia and May Be Potential Markers for the Assessment of PE Severity
TL;DR: In this article, a case-control study was designed to assess whether the serum levels of albumin (ALB), total protein (TP), prealbumin (PA), alkaline phosphatase (ALP), lactic dehydrogenase (LDH), D-dimer, fibrinogen (Fbg), platelet (PLT) count, mean platelet volume (MPV), and platelet distribution width (PDW) can help in assessing PE and evaluate its severity.
Adoptive Transfer of Paternal Antigen-Hyporesponsive T Cells Induces Maternal Tolerance to the Allogeneic Fetus in Abortion-Prone Matings
Li-Ping Jin,Da-Jin Li,Jin-Ping Zhang,Ming-Yan Wang,Xiao-Yong Zhu,Ying Zhu,Yi Meng,Min-Min Yuan +7 more
TL;DR: It is demonstrated that costimulation blockade with anti-B7 mAbs at the time of implantation resulted in altered allogeneic T cell response and overcame increased maternal rejection to the fetus in the CBA/J×DBA/2 system.