Ming X. Li
The Chinese University of Hong Kong
5 Papers
Ming X. Li is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Autophagy & Cancer. The author has an hindex of 5, co-authored 5 publications.
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Papers
Cigarette smoking and gastrointestinal diseases: The causal relationship and underlying molecular mechanisms (Review)
Long Fei Li,Ruby L. Y. Chan,Li Fang Lu,Jing Shen,Lina Zhang,William K.K. Wu,Lijun Wang,Tao Hu,Ming X. Li,Chi Hin Cho +9 more
TL;DR: The mechanisms through which cigarette smoking induces tumorigenesis and promotes the development of cancer in various sections of the GI tract are summarized and may help develop more effective therapies for GI disorders in the future.
Autophagy in intracellular bacterial infection.
Wei Hu,Hung Chan,Lan Lu,Kam Tak Wong,Sunny H. Wong,Ming X. Li,Zhan G. Xiao,Chi H. Cho,Tony Gin,Matthew T. V. Chan,William K.K. Wu,Lin Zhang +11 more
TL;DR: The current knowledge about the general mechanisms of intracellular bacterial infections and xenophagy is summarized and the ongoing battle between these two processes is focused on.
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Critical Role of Antimicrobial Peptide Cathelicidin for Controlling Helicobacter pylori Survival and Infection.
Lin Zhang,William K.K. Wu,Richard L. Gallo,Evandro Fei Fang,Wei Hu,Thomas K. W. Ling,Jing Shen,Ruby L. Y. Chan,Lan Lu,Xiao M. Luo,Ming X. Li,Kam Ming Chan,Jun Yu,Vincent Wai-Sun Wong,Siew C. Ng,Sunny H. Wong,Francis K.L. Chan,Joseph J.Y. Sung,Matthew T. V. Chan,Chi H. Cho +19 more
TL;DR: Findings indicate that cathelicidin plays a significant role as a potential natural antibiotic for H. pylori clearance and a therapeutic agent for chronic gastritis.
Reduced lysosomal clearance of autophagosomes promotes survival and colonization of Helicobacter pylori.
Lin Zhang,Wei Hu,Chi H. Cho,Francis K.L. Chan,Jun Yu,J. Ross Fitzgerald,Cynthia K. Cheung,Zhan G. Xiao,Jing Shen,Long F Li,Ming X. Li,Justin C.Y. Wu,Thomas K. W. Ling,Jason Y. K. Chan,Ho Ko,Gary Tse,Siew C. Ng,Sidney Yu,Maggie Ht Wang,Tony Gin,Hassan Ashktorab,Duane T. Smoot,Sunny H. Wong,Matthew T. V. Chan,William K.K. Wu +24 more
TL;DR: It is shown that H. pylori inhibited lysosomal function and thereby promoted the accumulation of autophagosomes in gastric epithelial cells, and subverts autophagy into a pro‐survival mechanism through inhibition of lysOSomal clearance ofautophagy.
Cathelicidin-encoding Lactococcus lactis promotes mucosal repair in murine experimental colitis.
Clover Ching Man Wong,Lin Zhang,William K.K. Wu,Jing Shen,Ruby L. Y. Chan,Lan Lu,Wei Hu,Ming X. Li,Long F Li,Shun Xiang Ren,Yi F Li,Jiang Li,Chi H. Cho +12 more
TL;DR: It is pivotal to understand the ability of N4I whether it can promote mucosal repair in existing colitis, as this data indicates that it may be important for the development of new treatments for colitis.
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