Ming Jiang
Guangxi Normal University
17 Papers
15 Citations
Ming Jiang is an academic researcher from Guangxi Normal University. The author has contributed to research in topics: Chemistry & Cisplatin. The author has an hindex of 3, co-authored 9 publications.
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Papers
Developing a Copper(II) Agent Based on His-146 and His-242 Residues of Human Serum Albumin Nanoparticles: Integration To Overcome Cisplatin Resistance and Inhibit the Metastasis of Nonsmall Cell Lung Cancer.
TL;DR: The anticancer mechanism of the C4/HSA-C4 NP multitargeting TME to overcome cisplatin resistance is confirmed: killing tumor cells by acting on the mtDNA and inducing apoptosis, polarizing M2-type macrophages to the M1-type, and inhibiting angiogenesis.
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Current status of iridium-based complexes against lung cancer
TL;DR: The recent progress of iridium complexes against lung cancer is summarized and their anti-tumor mechanisms are introduced, including apoptosis, cycle arrest, inhibition of lung cancer cell migration, induction of immunogenic cell death, etc.
Developing a Novel Indium(III) Agent Based on Liposomes to Overcome Cisplatin-Induced Resistance in Breast Cancer by Multitargeting the Tumor Microenvironment Components.
TL;DR: Wang et al. as discussed by the authors developed a novel indium (In) agent based on liposomes (Lips), which not only obtained an In(III) thiosemicarbazone agent (5b) with remarkable cytotoxicity, but also successfully constructed a novel 5b-loaded Lip(5b-Lip) delivery system.
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Human Serum Albumin-Based Dual-Agent Delivery Systems for Combination Therapy: Acting against Cancer Cells and Inhibiting Neovascularization in the Tumor Microenvironment.
TL;DR: The HSA conjugate not only possessed a stronger capacity to inhibit neovascularization and the growth of liver tumor but also improved the targeting ability compared to the combination of two agents alone.
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Synthesis of a series of novel In(III) 2,6-diacetylpyridine bis(thiosemicarbazide) complexes: structure, anticancer function and mechanism.
Shanhe Li,Muhammad Hamid Khan,Wang Xiaojun,Meiling Cai,Juzheng Zhang,Ming Jiang,Zhenlei Zhang,Xiaoan Wen,Hong Liang,Feng Yang +9 more
TL;DR: Interestingly, C4 not only showed higher cytotoxicity to cancer cells and less toxicity toward normal cells relative to cisplatin but also inhibited cell invasion and metastasis of T-24 cells, suggesting that C4 may be developed as a potential multi-functional and multi-targeting anticancer candidate.
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