Ming Ding
University of Pittsburgh
29 Papers
1K Citations
Ming Ding is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Viral load & Virus. The author has an hindex of 15, co-authored 26 publications.
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Papers
High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors.
Charles R. Rinaldo,Xiao Li Huang,Zheng Fan,Ming Ding,L Beltz,Alison J. Logar,D Panicali,G Mazzara,J Liebmann,M Cottrill +9 more
TL;DR: In this paper, the authors found that lack of disease in long-term non-progressors with human immunodeficiency virus type 1 (HIV-1) infection was strongly associated with very low copy numbers of HIV-1 DNA and RNA in peripheral blood mononuclear cells and plasma and the presence of high levels of anti-HIV1 CD8+ memory cytotoxic T lymphocytes specific for Gag, Pol, and Env, compared with levels present in intermediate and advanced progressors.
537
Human immunodeficiency virus type 1 shedding pattern in semen correlates with the compartmentalization of viral Quasi species between blood and semen.
Phalguni Gupta,Caroline Leroux,Bruce K. Patterson,Lawrence A. Kingsley,Charles R. Rinaldo,Ming Ding,Yue Chen,Kathy Kulka,William Buchanan,Brian M. McKeon,Ronald C. Montelaro +10 more
TL;DR: It is indicated for the first time that HIV-1 is shed primarily in an intermittent manner and that shedding patterns of HIV- 1 in semen are related to compartmentalization of HIV, type 1, between semen and blood.
154
Subcompartmentalization of HIV-1 quasispecies between seminal cells and seminal plasma indicates their origin in distinct genital tissues.
Shirish Paranjpe,Jodi K. Craigo,Bruce K. Patterson,Ming Ding,Paulo Feijó Barroso,Lee H. Harrison,Ronald C. Montelaro,Phalguni Gupta +7 more
TL;DR: Findings provide for the first time evidence of subcompartmentalization of HIV-1 in male genital organs and suggest that intervention strategies such as vasectomy may not prevent sexual transmission.
103
Noncytotoxic suppression of human immunodeficiency virus type 1 transcription by exosomes secreted from CD8+ T cells.
Ashwin Tumne,Varsha Shridhar Prasad,Yue Chen,Donna B. Stolz,Kunal Saha,Deena Ratner,Ming Ding,Simon C. Watkins,Phalguni Gupta +8 more
TL;DR: The results, for the first time, indicate the existence of an antiviral membrane-bound factor consistent with the hallmarks defining noncytotoxic CD8+ T-cell suppression of HIV-1.
84
Enhanced Expression of Human Immunodeficiency Virus Type 1 Correlates with Development of AIDS
Phalguni Gupta,Lawrence A. Kingsley,John A. Armstrong,Ming Ding,Martin Cottrill,Charles R. Rinaldo +5 more
TL;DR: The results support the role of HIV-1 RNA expression in the development of AIDS as the number of circulating CD4+ T-lymphocytes producing HIV- 1 increased and the level of proviral DNA was significantly higher in AIDS patients than in men who remained asymptomatic.
81