5 Papers
Min Yao is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Medicine & Pyroptosis. The author has an hindex of 1, co-authored 1 publications.
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Papers
NLRP3 Inflammasome Activation by MicroRNA-495 Promoter Methylation May Contribute to the Progression of Acute Lung Injury
Youguo Ying,Yong Mao,Min Yao +2 more
TL;DR: Elevated miR-495 alleviated lung injury and reduced the neutrophil infiltration and inflammation in rat models of LPS-induced ALI, which provides novel therapeutic targets for ALI treatment.
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HSP70 Ameliorates Septic Lung Injury via Inhibition of Apoptosis by Interacting with KANK2
TL;DR: Treatment with HSP70 ameliorated the survival rate, dysfunction of lung, inflammation, and apoptosis in cecal ligation and puncture-treated mice as well as in LPS-treated human alveolar epithelial cells and interaction with KANK2 played an important role in protection of acute lung injury caused by sepsis.
HSP70 alleviates sepsis-induced cardiomyopathy by attenuating mitochondrial dysfunction-initiated NLRP3 inflammasome-mediated pyroptosis in cardiomyocytes
Chenlu Song,Yiqiu Zhang,Qing-guo Pei,Li Zheng,Meiyu Wang,You-Zhen Shi,Shan Wu,Wei Ni,Xiu-Jun Fu,Yinbo Peng,Wen Zhang,Min Yao +11 more
TL;DR: In this paper , the authors investigated whether heat shock proteins (HSPs) can attenuate cellular mitochondrial dysfunction, exuberated inflammation and inflammasome-mediated pyroptosis for SIC intervention.
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HSP70 Ameliorates Septic Acute Kidney Injury via Binding with TRAF6 to Inhibit of Inflammation-Mediated Apoptosis
TL;DR: It is demonstrated that HSP70 played a critical role in sepsis-induced AKI via interaction with TRAF6 and inhibiting inflammation and apoptosis through interaction with tumor necrosis factor receptor-associated factor 6.
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Venovenous extracorporeal membrane oxygenation promotes alveolar epithelial recovery by activating Hippo/YAP signaling after lung injury.
Jian Huang,Rongzhi Zhang,Kerong Zhai,Jian Li,Min Yao,Shilin Wei,Xingdong Cheng,Jian Lin Yang,Bingren Gao,Xiangyang Wu,Yongnan Li +10 more
TL;DR: In this paper , the authors investigated the role of VV ECMO in preventing lung injury in vivo using a rat model and found that the Hippo/YAP signaling activation was associated with increased nuclear expression of YAP in alveolar epithelial type II cells.