Min Wang
Chinese Academy of Sciences
6 Papers
12 Citations
Min Wang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Neurogenesis & Biology. The author has an hindex of 6, co-authored 6 publications.
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Papers
Neural Stem Cells Behave as a Functional Niche for the Maturation of Newborn Neurons through the Secretion of PTN.
TL;DR: It is shown that adult hippocampal NSCs continuously supply pleiotrophin factor to the newborn neurons and behave as a functional niche for newly generated newborn neurons to regulate their maturation.
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Fragile X Proteins FMRP and FXR2P Control Synaptic GluA1 Expression and Neuronal Maturation via Distinct Mechanisms.
Weixiang Guo,Weixiang Guo,Eric D. Polich,Juan Su,Yu Gao,Devin M. Christopher,Andrea M. Allan,Min Wang,Feifei Wang,Guangfu Wang,Xinyu Zhao +10 more
TL;DR: It is discovered thatFXR2P (also known as FXR2) is important for neuronal dendritic development and a regulatory mechanism of GluA1 is uncovered, which reveals a functional convergence between fragile X proteins in neuronal development.
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The lysine catabolite saccharopine impairs development by disrupting mitochondrial homeostasis.
Junxiang Zhou,Junxiang Zhou,Xin Wang,Min Wang,Yuwei Chang,Fengxia Zhang,Zhaonan Ban,Ruofeng Tang,Qiwen Gan,Shaohuan Wu,Ye Guo,Qian Zhang,Fengyang Wang,Liyuan Zhao,Yudong Jing,Wenfeng Qian,Guodong Wang,Weixiang Guo,Chonglin Yang,Chonglin Yang +19 more
TL;DR: The requirement for mitochondrial saccharopine degradation in mitochondrial homeostasis and animal development is reported and mechanistic and therapeutic insights for understanding and treating hyperlysinemia II (saccharopinuria), an aminoacidopathy with severe developmental defects are provided.
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Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis.
Yuhan Wang,Ye Guo,Changyong Tang,Xiu Han,Mingyue Xu,Jing Sun,Yi-Fei Zhao,Yiwen Zhang,Min Wang,Xiaofeng Cao,Xiaojuan Zhu,Weixiang Guo +11 more
TL;DR: It is shown that the ablation of RNA-binding protein HuR in NSCs impairs adult but not embryonic neurogenesis, and mechanistic insights are provided into the differential regulation of embryonic and adult Neurogenesis through developmental cytoplasmic-to-nuclear translocation of HuR.
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Interplay between FMRP and lncRNA TUG1 regulates axonal development through mediating SnoN-Ccd1 pathway.
TL;DR: It is reported that FMRP directly interacted with lncRNA TUG1, and decreased its stability, and suggested interplay between FMRp and lncRNAs might contribute to the pathogenesis of FXS.