27 Papers
76 Citations
Min Sun is an academic researcher from Nanjing Agricultural University. The author has contributed to research in topics: Biology & Virus. The author has an hindex of 10, co-authored 23 publications.
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Papers
The Hcp proteins fused with diverse extended-toxin domains represent a novel pattern of antibacterial effectors in type VI secretion systems.
TL;DR: A new family of T6SS effectors encoded by extended Hcps carrying diverse toxin domains, designated as Hcp-ET, exist widely in the Enterobacteriaceae and demonstrated that both of these toxins had antibacterial effects.
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PAAR-Rhs proteins harbor various C-terminal toxins to diversify the antibacterial pathways of type VI secretion systems.
TL;DR: A novel Rhs with an MPTase4 (Metallopeptidase-4) domain that showed an antibacterial effect via T6SS in Escherichia coli is identified and various toxin/immunity pairs in extensive bacterial species that could be systematically classified into eight referential clans are discovered, suggesting that Rhs-CTs greatly diversify the antibacterial pathways of T 6SS.
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Two Functional Type VI Secretion Systems in Avian Pathogenic Escherichia coli Are Involved in Different Pathogenic Pathways
TL;DR: Results suggested that T6SS1 was involved in the proliferation of APEC in systemic infection, whereas VgrG-T6SS2 was responsible only for cerebral infection.
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Diverse toxic effectors are harbored by vgrG islands for interbacterial antagonism in type VI secretion system
TL;DR: A new retrieval strategy for screening T6SS effectors is reported, and an example how pathogenic bacteria antagonize and displace commensal microbiome to successfully colonize in the host niches through a T 6SS-dependent manner is provided.
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Genetic diversity and features analysis of type VI secretion systems loci in avian pathogenic Escherichia coli by wide genomic scanning
TL;DR: Comprehensive analysis showed prominent characteristics of T6SS1 locus, including wildly prevalence, rich sequence diversity, versatile VgrG islands and excellent expression competence in various E. coli pathotypes.
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