Min Guan
Soochow University (Suzhou)
3 Papers
Min Guan is an academic researcher from Soochow University (Suzhou). The author has contributed to research in topics: Drug carrier & Caco-2. The author has an hindex of 3, co-authored 3 publications.
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Papers
Low-density lipoprotein-coupled N-succinyl chitosan nanoparticles co-delivering siRNA and doxorubicin for hepatocyte-targeted therapy
Qiao-Ling Zhu,Yi Zhou,Min Guan,Xiao-feng Zhou,Shu-di Yang,Yang Liu,Wei-liang Chen,Chun-ge Zhang,Zhi-qiang Yuan,Chun Liu,Aijun Zhu,Xue-nong Zhang +11 more
TL;DR: Results indicated that LDL-SCS-NPs were effective tumor-targeting vectors and that the preparation form may provide a new strategy for co-delivering siRNA and antitumor drugs.
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N-trimethyl chitosan nanoparticle-encapsulated lactosyl-norcantharidin for liver cancer therapy with high targeting efficacy
TL;DR: The preparation of N-trimethyl chitosan-encapsulated lactosyl-norcantharidin TMC nanoparticles is described that displayed efficient targeting and sustained release in a hepatocarcinoma SC murine model and had the strongest antitumor activity on the murine hepatocARCinoma 22 subcutaneous model.
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Uptake and transport of a novel anticancer drug-delivery system: lactosyl-norcantharidin-associated N-trimethyl chitosan nanoparticles across intestinal Caco-2 cell monolayers.
TL;DR: The continuous line of heterogeneous human epithelial colorectal adenocarcinoma cells (Caco-2) cell monolayer model was used to study the transport mechanism of Lac-NCTD, and the effects of factors such as time, temperature, pH level, drug concentration, enhancers, and inhibitors were studied.