Miklós Tóth
Stockholm County Council
5 Papers
6 Citations
Miklós Tóth is an academic researcher from Stockholm County Council. The author has contributed to research in topics: Imaging phantom & Gene silencing. The author has an hindex of 3, co-authored 5 publications.
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Papers
Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease
Bryan Zeitler,Steven Froelich,Kimberly Marlen,David A. Shivak,Qi Yu,Davis Li,Jocelynn R. Pearl,Jeffrey C. Miller,Lei Zhang,David Paschon,Sarah J. Hinkley,Irina Ankoudinova,Stephen Lam,Dmitry Guschin,Lexi Kopan,Jennifer M. Cherone,Hoang Oanh B. Nguyen,Guijuan Qiao,Yasaman Ataei,Matthew C. Mendel,Rainier Amora,Richard T. Surosky,Josee Laganiere,B. Joseph Vu,Anand Narayanan,Yalda Sedaghat,Karsten Tillack,Christina Thiede,Annette Gärtner,Seung Kwak,Jonathan Bard,Ladislav Mrzljak,Larry Park,Taneli Heikkinen,Kimmo Lehtimäki,Marie Svedberg,Jenny Haggkvist,Lenke Tari,Miklós Tóth,Andrea Varrone,Christer Halldin,Andrea E. Kudwa,Sylvie Ramboz,Michelle Day,Jyothisri Kondapalli,D. James Surmeier,Fyodor D. Urnov,Philip D. Gregory,Edward J. Rebar,Ignacio Munoz-Sanjuan,H. Steve Zhang +50 more
TL;DR: Improvements in a range of molecular, histopathological, electrophysiological and functional endpoints are demonstrated and support the continued development of an allele-selective ZFP-TF for the treatment of Huntington’s disease.
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Performance Evaluation of a High-Resolution Nonhuman Primate PET/CT System.
Zsolt Sarnyai,Kalman Nagy,G. Patay,Milán Molnár,Göran Rosenqvist,Miklós Tóth,Akihiro Takano,Balázs Gulyás,Balázs Gulyás,Peter Major,Christer Halldin,Christer Halldin,Andrea Varrone +12 more
TL;DR: The results obtained from phantom experiments and 1 representative PET measurement in an NHP confirm that the LFER 150 is a high-resolution PET/CT system with suitable performance for brain imaging in NHPs.
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The MINDVIEW project: First results.
Jose M. Benlloch,Antonio González,Roberto Pani,Enrico Preziosi,Carl Jackson,John W. Murphy,Julio Barbera,C. Correcher,Sebastian Aussenhofer,Daniel Gareis,Dimitris Visvikis,Julien Bert,Bengt Långström,Lars Farde,Miklós Tóth,Jenny Haggkvist,Fabio Viegas Caixeta,Klas Kullander,Ian Somlai-Schweiger,Markus Schwaiger +19 more
TL;DR: It has been shown that 11C-raclopride has higher binding potential in a new VAAT null mutant mouse model of schizophrenia compared to wild type control animals, and a significant reduction in TSPO binding has been found in gray matter in a small sample of drug-naïve, first episode psychosis patients.
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PET Imaging of VMAT2 with the Novel Radioligand [18F]FE-DTBZ-d4 in Nonhuman Primates: Comparison with [11C]DTBZ and [18F]FE-DTBZ.
TL;DR: In this article, the brain kinetics and quantification of [18F]FE-DTBZ-d4 in nonhuman primates (NHPs) were investigated, with comparison to [11C] DTBZ and [18 F ]FE-DTZ-D4, which showed similar imaging properties with better stability against defluorination.
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Multiple Applications of a Novel Biarsenical Imaging Probe in Fluorescence and PET Imaging of Melanoma.
Mikhail Kondrashov,Samuel P.S. Svensson,Peter Ström,Andreas Westermark,Hanna Jacobson-Ingemyr,Akihiro Takano,Lenke Tari,Miklós Tóth,Minying Cai,Victor J. Hruby,Magnus Schou,Magnus Schou +11 more
TL;DR: A new fluorescent biarsenical peptide labeling probe was synthesized and labeled with the radioactive isotopes 11C and 18F in this article, which targets melanoma tumors.
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