Mikhail Rotkevich
Saint Petersburg State University
9 Papers
16 Citations
Mikhail Rotkevich is an academic researcher from Saint Petersburg State University. The author has contributed to research in topics: Mycobacterium tuberculosis & Tuberculosis. The author has an hindex of 4, co-authored 9 publications.
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Papers
Genome-wide Mycobacterium tuberculosis variation (GMTV) database: a new tool for integrating sequence variations and epidemiology
Ekaterina Chernyaeva,M Shul'gina,Mikhail Rotkevich,Pavel Dobrynin,Serguei Simonov,Egor Shitikov,Dmitry S. Ischenko,Irina Y. Karpova,Elena S. Kostryukova,Elena N. Ilina,Vadim M. Govorun,Vyacheslav Y. Zhuravlev,Olga Manicheva,Peter K Yablonsky,Yulia D Isaeva,Elena Nosova,Igor Mokrousov,Anna Vyazovaya,Olga Narvskaya,Alla Lapidus,Alla Lapidus,Stephen J. O'Brien +21 more
TL;DR: A broadly inclusive unifying Genome-wide Mycobacterium tuberculosis Variation (GMTV) database, (http://mtb.dobzhanskycenter.org) that catalogues genome variations of M. tuberculosis strains collected across Russia, facilitates disease gene discoveries associated with drug resistance or different clinical sequelae, and automates comparative genomic analyses among M. TB strains.
Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia.
Ekaterina Chernyaeva,Mikhail Rotkevich,Ksenia Krasheninnikova,Andrey A. Yurchenko,Anna Vyazovaya,Igor Mokrousov,Natalia Solovieva,Viacheslav Zhuravlev,Piotr Yablonsky,Stephen J. O'Brien +9 more
TL;DR: Whole-genome analysis of Mycobacterium tuberculosis isolates collected in Russia supports a detailed characterization of pathogen strain distributions and drug resistance phenotype, plus distinguished occurrence and association of known resistance mutations.
Analytical "bake-off" of whole genome sequencing quality for the Genome Russia project using a small cohort for autoimmune hepatitis.
Daria V. Zhernakova,Daria V. Zhernakova,Sergei Kliver,Nikolay Cherkasov,Gaik Tamazian,Mikhail Rotkevich,Ksenia Krasheninnikova,Igor Evsyukov,Sviatoslav Sidorov,Pavel Dobrynin,Andrey A. Yurchenko,Valentin Shimansky,Irina V. Shcherbakova,Andrey S. Glotov,David Valle,Minzhong Tang,Emilia Shin,Kathleen B. Schwarz,Stephen J. O'Brien,Stephen J. O'Brien +19 more
TL;DR: A comparative analysis of whole genome sequencing (WGS) and genotype calling was initiated for ten human genome samples sequenced by St. Petersburg State University Peterhof Sequencing Center and by three commercial sequencing centers outside of Russia, showing high similarities among the sequence quality and called genotypes.
Mycobacterium bovis in Panama, 2013.
Fermín Acosta,Ekatherina Chernyaeva,Libardo Mendoza,Dilcia Sambrano,Ricardo Correa,Mikhail Rotkevich,Miroslava Tarté,Humberto Hernández,Bredio Velazco,Cecilia de Escobar,Jacobus H. de Waard,Amador Goodridge +11 more
TL;DR: DNA fingerprinting of 7 M. bovis isolates from a 2013 bovine tuberculosis outbreak indicated minimal homology with strains previously circulating in Panama, highlighting the need for enhanced genotype testing to track zoonotic infections.
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GWATCH: a web platform for automated gene association discovery analysis
Anton Svitin,Sergey V. Malov,Nikolay Cherkasov,Paul Geerts,Mikhail Rotkevich,Pavel Dobrynin,Andrey Shevchenko,Li Guan,Jennifer L. Troyer,Sher L. Hendrickson,Holli H. Dilks,Taras K. Oleksyk,Sharyne M. Donfield,Edward D. Gomperts,Douglas A. Jabs,Efe Sezgin,Mark L. Van Natta,P. Richard Harrigan,Zabrina L. Brumme,Stephen J. O'Brien,Stephen J. O'Brien +20 more
TL;DR: The utility of GWATCH is illustrated with three large genome-wide association studies for HIV-AIDS resistance genes screened in large multicenter cohorts; however, association datasets from any study can be uploaded and analyzed by GWATCH.