Mikako Ogawa
Hokkaido University
154 Papers
1.2K Citations
Mikako Ogawa is an academic researcher from Hokkaido University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 40, co-authored 141 publications. Previous affiliations of Mikako Ogawa include Promega & Kyoto University.
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Papers
New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging
TL;DR: Although MRI, US, and x-ray CT are often listed as molecular imaging modalities, in truth, radionuclide and optical imaging are the most practical modalities for molecular imaging, because of their sensitivity and the specificity for target detection.
Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules
Makoto Mitsunaga,Mikako Ogawa,Nobuyuki Kosaka,Lauren T Rosenblum,Peter L. Choyke,Hisataka Kobayashi +5 more
TL;DR: A new type of molecular-targeted cancer therapy, photoimmunotherapy (PIT), that uses a target-specific photosensitizer based on a near-infrared (NIR) phthalocyanine dye, IR700, conjugated to monoclonal antibodies (mAbs) targeting epidermal growth factor receptors is developed.
Toxicity of organic fluorophores used in molecular imaging: literature review.
Raphael Alford,Haley M. Simpson,Josh Duberman,G. Craig Hill,Mikako Ogawa,Celeste A. S. Regino,Hisataka Kobayashi,Peter L. Choyke +7 more
TL;DR: A review of published literature on the toxicity of 19 widely used fluorophores was conducted by searching 26 comprehensive biomedical and chemical literature databases and analyzing the retrieved material.
465
Rapid Cancer Detection by Topically Spraying a γ-Glutamyltranspeptidase–Activated Fluorescent Probe
Yasuteru Urano,Masayo Sakabe,Nobuyuki Kosaka,Mikako Ogawa,Makoto Mitsunaga,Daisuke Asanuma,Mako Kamiya,Matthew R. Young,Tetsuo Nagano,Peter L. Choyke,Hisataka Kobayashi +10 more
TL;DR: A rapidly activatable, cancer-selective fluorescence imaging probe that fluoresces upon cleavage by a cancer-specific enzyme and can be used during surgical or endoscopic tumor removal procedures, and several other aminopeptidase–based reagents identified by the authors could help surgeons to track down tiny tumors dispersed throughout body cavities.
438
Sensitive β-galactosidase-targeting fluorescence probe for visualizing small peritoneal metastatic tumours in vivo
Daisuke Asanuma,Masayo Sakabe,Mako Kamiya,Kyoko Yamamoto,Jun Hiratake,Mikako Ogawa,Nobuyuki Kosaka,Peter L. Choyke,Tetsuo Nagano,Hisataka Kobayashi,Yasuteru Urano +10 more
TL;DR: The results clearly indicate preclinical potential value of the probe for fluorescence-guided diagnosis of peritoneal metastases from ovarian cancers and endoscopic fluorescence detection of metastases is demonstrated.