Miguel A. Piris

TL;DR: It is found that cancer cells had a loss of monoacetylated and trimethylated forms of histone H4 early and accumulated during the tumorigenic process, which is a common hallmark of human tumor cells.

TL;DR: The patterns of somatic mutation, supported by functional and clinical analyses, strongly indicate that the recurrent NOTCH1, MYD88 and XPO1 mutations are oncogenic changes that contribute to the clinical evolution of the disease.

TL;DR: The definition, recommended studies, and criteria for the diagnosis of many entities have been extensively refined and some categories considered provisional are now upgraded to definite entities in the proposed International Consensus Classification of mature lymphoid, histiocytic, and dendritic cell tumors.

TL;DR: It is concluded that MYC/BCL2 coexpression in DLBCL is associated with an aggressive clinical course, is more common in the ABC subtype, and contributes to the overall inferior prognosis of patients with ABC-DLBCL.