Mie Østergaard Pedersen
University of Copenhagen
11 Papers
102 Citations
Mie Østergaard Pedersen is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Neuroprotection & Neuroinflammation. The author has an hindex of 10, co-authored 11 publications.
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Papers
Metallothionein-I+II in neuroprotection
Mie Østergaard Pedersen,Rikke Anker Jensen,Dan Sonne Pedersen,Dan Sonne Pedersen,Anders D. Skjolding,Casper Hempel,Casper Hempel,Lasse Maretty,Lasse Maretty,Milena Penkowa +9 more
TL;DR: The newest data on cerebral MT‐I+II functions following brain injury and experimental autoimmune encephalomyelitis are discussed, with a focus on the neuroprotective functions of the central nervous system.
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Gold ions bio-released from metallic gold particles reduce inflammation and apoptosis and increase the regenerative responses in focal brain injury
Agnete Larsen,Kristian Kolind,Dan Sonne Pedersen,P. Doering,Mie Østergaard Pedersen,Gorm Danscher,Milena Penkowa,Meredin Stoltenberg +7 more
TL;DR: It is concluded that bio-liberated gold ions possess pronounced anti-inflammatory and neuron-protective capacities in the brain and it is suggested that metallic gold has clinical potentials.
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Cell death in the injured brain: roles of metallothioneins.
TL;DR: An overview of the TBI pathophysiology leading to cell death and neurological impairment is provided and endogenously expressed neuroprotectants and drug candidates, which at this stage may still hold the potential for treating brain injured patients are discussed.
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Metallic gold treatment reduces proliferation of inflammatory cells, increases expression of VEGF and FGF, and stimulates cell proliferation in the subventricular zone following experimental traumatic brain injury.
TL;DR: In this article, the effects of gold-treatment were investigated by examining gold-induced growth factor expression (VEGF and FGF) in the first two weeks after the insult, and the extent of the neurostimulatory effect of gold was explored by comparing cell proliferation in the subventricular zone as judged by immunohistochemical staining for CDC47.
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Metallic gold slows disease progression, reduces cell death and induces astrogliosis while simultaneously increasing stem cell responses in an EAE rat model of multiple sclerosis
Dan Sonne Pedersen,Dan Sonne Pedersen,Pil Møntegaard Fredericia,Mie Østergaard Pedersen,Meredin Stoltenberg,Milena Penkowa,Gorm Danscher,Jørgen Rungby,Agnete Larsen +8 more
TL;DR: This study is the first to show that the presence of small gold implants affect disease progression in a rat model of MS, increasing the neurogenic response and reducing the loss of cells in disease foci.
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