Micol Massimiani
University of Rome Tor Vergata
29 Papers
26 Citations
Micol Massimiani is an academic researcher from University of Rome Tor Vergata. The author has contributed to research in topics: Trophoblast & Medicine. The author has an hindex of 10, co-authored 20 publications. Previous affiliations of Micol Massimiani include International University, Cambodia.
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Papers
Molecular Signaling Regulating Endometrium–Blastocyst Crosstalk
Micol Massimiani,Micol Massimiani,Valentina Lacconi,Fabio La Civita,Carlo Ticconi,Rocco Rago,Luisa Campagnolo +6 more
TL;DR: The aim of this review is to give an overview of the factors and mechanisms regulating implantation, with a focus on those involved in the complex crosstalk between the blastocyst and the endometrium.
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Silver nanoparticles inhaled during pregnancy reach and affect the placenta and the foetus
Luisa Campagnolo,Micol Massimiani,Lucia Vecchione,Diletta Piccirilli,Nicola Toschi,Andrea Magrini,Elena Bonanno,Manuel Scimeca,Luca Castagnozzi,Giorgio Buonanno,Luca Stabile,Francesco Cubadda,Federica Aureli,Paul H. B. Fokkens,Wolfgang G. Kreyling,Flemming R. Cassee,Antonio Pietroiusti +16 more
TL;DR: It is proved that NPs are able to reach and cross the mouse placenta and suggest that precaution should be taken with respect to acute exposure to nanoparticles during pregnancy.
Epidermal growth factor-like domain 7 promotes migration and invasion of human trophoblast cells through activation of MAPK, PI3K and NOTCH signaling pathways
Micol Massimiani,Lucia Vecchione,Diletta Piccirilli,Paola Spitalieri,Francesca Amati,Silvia Salvi,Sergio Ferrazzani,Heidi Stuhlmann,Luisa Campagnolo +8 more
TL;DR: The data suggest that in trophoblast cells, EGFL7 regulates cell migration and invasion by activating multiple signaling pathways, and provides a possible explanation for the correlation between reduced expression of EG FL7 and inadequate trophOBlast invasion observed in placentopathies.
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Physico-Chemical Properties Mediating Reproductive and Developmental Toxicity of Engineered Nanomaterials
TL;DR: A critical analysis of the published work on reproductive and developmental toxicity of the most commonly used nanoparticles with a major focus on mammalian models is performed, placing emphasis on the main physico-chemical characteristics that can affect NP behaviour in biological systems.
Novel expression of EGFL7 in placental trophoblast and endothelial cells and its implication in preeclampsia
Lauretta A. Lacko,Micol Massimiani,Jenny L. Sones,Romulo Hurtado,Silvia Salvi,Sergio Ferrazzani,Robin L. Davisson,Luisa Campagnolo,Heidi Stuhlmann +8 more
TL;DR: It is shown that Egfl7 is expressed by the endothelium of both the maternal and fetal vasculature throughout placental development, and a previously unknown site of EGFL7 expression in the trophoblast cell lineage is uncovered, including the trophectoderm, troPHoblast stem cells, and placental trophoblasts.
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