Michelle Abboud
Memorial Sloan Kettering Cancer Center
10 Papers
19 Citations
Michelle Abboud is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Transplantation & Cord blood. The author has an hindex of 5, co-authored 10 publications.
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Papers
Cord blood units with low CD34+ cell viability have a low probability of engraftment after double unit transplantation.
Andromachi Scaradavou,Katherine Smith,Rebecca Hawke,Allison Schaible,Michelle Abboud,Nancy A. Kernan,James W. Young,Juliet N. Barker +7 more
TL;DR: The data suggests one mechanism by which double unit CBT can improve engraftment is by increasing the probability of transplanting at least one unit with adequate viability and the potential to engraft.
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A “No-wash” Albumin-Dextran Dilution Strategy for Cord Blood Unit Thaw: High Rate of Engraftment and a Low Incidence of Serious Infusion Reactions
Juliet N. Barker,Michelle Abboud,R.D. Rice,Rebecca Hawke,Allison Schaible,Glenn Heller,Vincent La Russa,Andromachi Scaradavou +7 more
TL;DR: CB thaw with albumin-dextran dilution reduces unit manipulation, and minimizes cell loss, speeds time to infusion, is associated with a tolerable infusion reaction profile, and a high rate of sustained engraftment in CBT recipients >or=20 kg.
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CD34+ Viability Is a Critical Determinant of the Engraftment Potential of Umbilical Cord Blood (UCB) in Double Unit Transplantation.
Andromachi Scaradavou,Katherine Smith,Rebecca Hawke,Sinda Lee,Allison Schaible,Michelle Abboud,Nancy H. Collins,Nancy A. Kernan,Marcel R.M. van den Brink,Juliet N. Barker +9 more
TL;DR: It is shown that superior CD34+ and CD3+ viability (measured by 7-AAD staining) would be associated with unit predominance, and 25/26 patients demonstrated donor engraftment by STR evaluation of day+21 bone marrow with one unit predominating (the “winner”).
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Vaccine Response In Recipients of HLA Mismatched Unrelated Double Unit Cord Blood Transplantation (CBT).
Trudy N. Small,Christine Scura Iovino,Michelle Abboud,Marissa Lubin,Esperanza B. Papadopoulos,Andromachi Scaradavou,Juliet N. Barker +6 more
TL;DR: Pre-vaccination titers obtained at a median of 1 year post-CBT demonstrated that over 85% of patients lacked protection against Pneumococcus, H. influenzae, and Pertussis, and at least 50% lacked immunity against tetanus, measles, and mumps.
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