Michael W. Danneman
Vanderbilt University
12 Papers
3 Citations
Michael W. Danneman is an academic researcher from Vanderbilt University. The author has contributed to research in topics: Enantioselective synthesis & Enantiomer. The author has an hindex of 5, co-authored 10 publications. Previous affiliations of Michael W. Danneman include Xavier University.
Chat about Author
Papers
Oxidative inter-/intermolecular alkene diamination of hydroxy styrenes with electron-rich amines.
TL;DR: Doubly intermolecular alkene diamination is achieved with electron-rich, terminal alkenes through the use of a hypervalent iodine (PhI(OAc)2) reagent, iodide, and electron- rich amines.
52
Chiral proton catalysis of secondary nitroalkane additions to azomethine: synthesis of a potent GlyT1 inhibitor.
TL;DR: The first enantioselective synthesis of a potent GlyT1 inhibitor is described, using a 3-nitroazetidine donor used in an enantiOSElective aza-Henry reaction catalyzed by a bis(amidine)-triflic acid salt organocatalyst.
49
A Unified Approach to the Four Azaindoline Families by Inter-/Intramolecular Annulative Diamination of Vinylpyridines
TL;DR: 3-Amino azaindolines are formed by the reaction of ortho-vinyl N-tosyl anilines with electron-rich amines using phenyliododiaceate (PIDA) and an iodide additive.
34
Total synthesis of (+)-pilosinine via a stereodivergent conjugate addition strategy.
Cassandra L. Schrank,Michael W. Danneman,Emily A. Prebihalo,Robert E. Anderson,Tyler J. Gibson,William M. Wuest,Richard J. Mullins +6 more
TL;DR: Through the application of stereodivergent reaction conditions, the total synthesis of (+)-pilosinine and the formal synthesis of (-)-pilesinine has been completed from a single enantiomer of the 1,3-oxazolidi-none auxiliary.
3
Organocatalytic, Diastereo‐ and Enantioselective Synthesis of Nonsymmetric cis‐Stilbene Diamines: A Platform for the Preparation of Single‐Enantiomer cis‐Imidazolines for Protein—Protein Inhibition.
Brandon A. Vara,Anand Mayasundari,John C. Tellis,Michael W. Danneman,Vanessa Arredondo,Tyler A. Davis,Jaeki Min,Kristin Finch,R. Kiplin Guy,Jeffrey N. Johnston +9 more
TL;DR: The novel mono(amidine) catalysts (+)-(I) and their enantiomers are found to be highly efficient for the syntheses of a broad spectrum of adducts in the enantioselective aza - Henry approach.
2