Michael W. Beresford
University of Liverpool
248 Papers
686 Citations
Michael W. Beresford is an academic researcher from University of Liverpool. The author has contributed to research in topics: Medicine & Lupus nephritis. The author has an hindex of 39, co-authored 231 publications. Previous affiliations of Michael W. Beresford include Boston Children's Hospital & University of Manchester.
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Papers
Disease activity, severity, and damage in the UK juvenile‐onset systemic lupus erythematosus cohort
L Watson,Valentina Leone,Clarissa Pilkington,Kjell Tullus,Satyapal Rangaraj,Janet E. McDonagh,Janet Gardner-Medwin,Nick Wilkinson,Phil Riley,Jane Tizard,Kate Armon,Manish D. Sinha,Yiannis Ioannou,Neil Archer,Kathryn Bailey,Joyce Davidson,Eileen Baildam,Gavin Cleary,Liza J McCann,Michael W. Beresford +19 more
TL;DR: The data on these patients from the UK JSLE Cohort Study indicate that severe organ involvement and significant disease activity are primary characteristics in children with juvenile SLE.
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Protein kinase cδ deficiency causes mendelian systemic lupus erythematosus with B cell-defective apoptosis and hyperproliferation.
Alexandre Belot,Paul R. Kasher,Eleanor W. Trotter,Anne Perrine Foray,Anne Laure Debaud,Gillian I. Rice,Marcin Szynkiewicz,Marie Therese Zabot,Isabelle Rouvet,Sanjeev S. Bhaskar,Sarah B. Daly,Jonathan E. Dickerson,Josephine Mayer,James O'Sullivan,Laurent Juillard,Jill E. Urquhart,Shameem Fawdar,Anna A. Marusiak,Natalie Stephenson,Bohdan Waszkowycz,Michael W. Beresford,Leslie G. Biesecker,Graeme C.M. Black,Céline René,Jean Francois Eliaou,Nicole Fabien,Bruno Ranchin,Pierre Cochat,Patrick M. Gaffney,Flore Rozenberg,Pierre Lebon,Christophe Malcus,Yanick J. Crow,John Brognard,Nathalie Bonnefoy +34 more
TL;DR: The findings indicate that PKCδ is crucial in regulating B cell tolerance and preventing self-reactivity in humans, and that PKcδ deficiency represents a novel genetic defect of apoptosis leading to SLE.
European evidence-based recommendations for diagnosis and treatment of childhood-onset systemic lupus erythematosus: the SHARE initiative
Noortje Groot,Noortje Groot,Nienke de Graeff,Tadej Avcin,Brigitte Bader-Meunier,Paul A. Brogan,Pavla Dolezalova,Brian M. Feldman,Isabelle Koné-Paut,Pekka Lahdenne,Stephen D. Marks,Liza J McCann,Seza Ozen,Clarissa Pilkington,Angelo Ravelli,Annet van Royen-Kerkhof,Yosef Uziel,Bas Vastert,Nico M Wulffraat,Sylvia Kamphuis,Michael W. Beresford +20 more
TL;DR: The SHARE recommendations for cSLE and neuropsychiatric manifestations of cSle have been formulated by an evidence-based consensus process to support uniform, high-quality standards of care for children with cSLET.
Juvenile idiopathic arthritis: from aetiopathogenesis to therapeutic approaches.
Lina N. Zaripova,Angela Midgley,Stephen E. Christmas,Michael W. Beresford,Eileen Baildam,Rachel A. Oldershaw +5 more
TL;DR: Juvenile idiopathic arthritis (JIA) is the most common paediatric rheumatological disorder and is classified by subtypes according to International League of Associations for Rheumatology criteria.
Juvenile-onset systemic lupus erythematosus: Update on clinical presentation, pathophysiology and treatment options.
Eve Mary Dorothy Smith,Eve Mary Dorothy Smith,Hanna Lythgoe,Angela Midgley,Michael W. Beresford,Christian M. Hedrich,Christian M. Hedrich +6 more
TL;DR: Future directions to improve the care of jSLE patients, including implementation of the Single Hub and Access point for pediatric Rheumatology in Europe (SHARE) recommendations, biomarkers, treat to target and personalized medicine approaches are discussed.
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